{"id":"W1975418052","doi":"10.1096/fj.05-4647fje","title":"Expression of Concern: Essential requirement for sphingosine kinase activity in eNOS‐dependent NO release and vasorelaxation","year":2005,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Enos; Sphingosine kinase; Sphingosine-1-phosphate; Chemistry; Sphingosine; Cell biology; Sphingosine kinase 1; Pharmacology; Biochemistry; Biology; Nitric oxide synthase; Enzyme; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":{"nature":"Expression of concern","reason":"Concerns/Issues about Data;Investigation by Company/Institution;","date":"2/14/2023 0:00","openalex_flagged":false},"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.000171584,0.0001915096,0.0002306751,0.00012482,0.0001828808,0.0003571046,0.0001424195,0.0002289129,0.002505562],"category_scores_gemma":[0.0001619723,0.0001147811,0.0002198741,0.0001142517,0.0001666892,0.0001641357,0.000231457,0.0003985522,0.000820525],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002770559,"about_ca_system_score_gemma":0.0002395194,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004615947,"about_ca_topic_score_gemma":0.0005776354,"domain_scores_codex":[0.9997607,0.00003358764,0.00002689957,0.00005706403,0.00005292004,0.00006881634],"domain_scores_gemma":[0.9998313,0.00002349617,0.00004490949,0.00002489425,0.00002162095,0.00005370617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006175617,0.0000166075,0.00007399778,0.00001400043,0.000001308568,0.00002720833,0.000008791222,0.000008609839,0.9992892,0.00007033082,0.00002753194,0.0004007202],"study_design_scores_gemma":[0.00001994984,0.0002394441,0.00703886,0.000008910903,0.00001441312,0.000445422,0.00004331405,0.0007033093,0.9866676,0.00008611851,0.004728194,0.000004445763],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.991719,0.001582938,0.003425759,0.0002776918,0.00005436596,0.00004445196,0.0008224893,0.00009566991,0.001977616],"genre_scores_gemma":[0.9921008,0.0007147482,0.001547133,0.00005868781,0.00001600233,0.00004373249,0.001347133,0.00002708643,0.004144697],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.9997711,"threshold_uncertainty_score":0.008381963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01571455021399463,"score_gpt":0.2677839072329596,"score_spread":0.2520693570189649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}