{"id":"W1975431885","doi":"10.1016/j.gene.2006.04.015","title":"The modification of Sp3 isoforms by SUMOylation has differential effects on the SRC1A promoter","year":2006,"lang":"en","type":"article","venue":"Gene","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"","keywords":"SUMO protein; Gene isoform; Biology; Promoter; Activator (genetics); Gene; Gene expression; Molecular biology; Computational biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003216809,0.0004171418,0.0004607864,0.0004401686,0.0002951034,0.0005294664,0.0003088047,0.000328156,0.001703618],"category_scores_gemma":[0.0003677925,0.0003545806,0.0006422187,0.0002584614,0.0005020926,0.0004086225,0.000389218,0.0009291538,0.000518262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004814496,"about_ca_system_score_gemma":0.0002902627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009589472,"about_ca_topic_score_gemma":0.001415613,"domain_scores_codex":[0.9996725,0.00005098552,0.00003230931,0.00007203969,0.00006447,0.000107644],"domain_scores_gemma":[0.9994997,0.0001274395,0.00007465657,0.00008672562,0.00006309358,0.0001483039],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001842587,0.00001170603,0.0001659232,0.00001104083,0.000004159305,0.00002624576,0.00001239129,0.00001842105,0.9988019,0.0001076104,0.00001479872,0.0006414177],"study_design_scores_gemma":[0.00001190064,0.0001016408,0.006404104,0.000003063333,0.00001547279,0.0002047915,0.00002979655,0.0004017932,0.9922349,0.00007286068,0.0005147695,0.000004797852],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954698,0.001322451,0.001530905,0.0001423825,0.00003699047,0.00000729655,0.0003216573,0.00004970989,0.001118818],"genre_scores_gemma":[0.9956275,0.0005492572,0.0008398311,0.00005475259,0.00001858973,0.00001458916,0.000645674,0.00005290047,0.002196777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001703618,"threshold_uncertainty_score":0.005699158,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01194198631182162,"score_gpt":0.216117256272005,"score_spread":0.2041752699601834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}