{"id":"W1975461562","doi":"10.1038/nchembio.525","title":"Chemical contrast for imaging living systems: molecular vibrations drive CARS microscopy","year":2011,"lang":"en","type":"review","venue":"Nature Chemical Biology","topic":"Spectroscopy Techniques in Biomedical and Chemical Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":226,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; Steacie Institute for Molecular Sciences","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Korea Research Institute of Standards and Science","keywords":"Biomolecule; Microscopy; Lipid droplet; Organelle; Biophysics; Molecular imaging; Nanotechnology; Chemistry; Biology; Materials science; Cell biology; Optics; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007326499,0.001135678,0.001277106,0.002095848,0.0002934506,0.000944099,0.001693905,0.00171038,0.0028654],"category_scores_gemma":[0.0006201096,0.0005135346,0.0003782232,0.00226198,0.001005206,0.001836152,0.0008994936,0.002540195,0.003398232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001028433,"about_ca_system_score_gemma":0.0007693307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001504552,"about_ca_topic_score_gemma":0.002541622,"domain_scores_codex":[0.9997857,0.0000213212,0.00001514929,0.00004400577,0.0001113721,0.00002255662],"domain_scores_gemma":[0.9996635,0.0001486215,0.00003585793,0.00001533106,0.0001055339,0.00003115813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004311452,0.00008724602,0.00006412574,0.006578529,0.00004661488,0.0001342935,0.00003266619,0.0004433698,0.01166443,0.007903665,0.04504475,0.9279572],"study_design_scores_gemma":[0.00001767893,0.00006052832,0.0003438375,0.0009087115,0.00004716712,0.001109108,0.00002858343,0.0003615132,0.005841467,0.003362486,0.9878761,0.00004275767],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001878968,0.9946273,0.001913724,0.0004709986,0.0005335741,0.00001171361,0.00002514087,0.00003765556,0.002191931],"genre_scores_gemma":[0.001794961,0.9913663,0.002256405,0.0005732757,0.0004443228,0.0000236316,0.00006529487,0.00001298248,0.003462715],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0028654,"threshold_uncertainty_score":0.009585738,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01287584998958822,"score_gpt":0.3702139273478976,"score_spread":0.3573380773583094,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}