{"id":"W1975463890","doi":"10.1128/jvi.01964-06","title":"Failure To Open the Blood-Brain Barrier and Deliver Immune Effectors to Central Nervous System Tissues Leads to the Lethal Outcome of Silver-Haired Bat Rabies Virus Infection","year":2006,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Rabies epidemiology and control","field":"Immunology and Microbiology","cited_by":119,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Biology; Rabies virus; Rabies; Central nervous system; Virology; Immune system; Blood–brain barrier; Mononegavirales; Rhabdoviridae; Effector; Lyssavirus; Virus; Immunology; Encephalitis; Immunity; Viral disease; Paramyxoviridae; Neuroscience","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002007986,0.0003380411,0.0003830629,0.0002448623,0.0001697023,0.000355836,0.0003278427,0.0004331898,0.001258115],"category_scores_gemma":[0.0002728702,0.0001708791,0.0002836734,0.0000993909,0.0004814567,0.0003182549,0.0003387954,0.001332536,0.0004902352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002724254,"about_ca_system_score_gemma":0.00019992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000869848,"about_ca_topic_score_gemma":0.001238706,"domain_scores_codex":[0.9996473,0.00004884843,0.00004016476,0.0000823148,0.00007698668,0.0001044435],"domain_scores_gemma":[0.9996294,0.00006733843,0.00009825765,0.00005992907,0.00003131191,0.0001137275],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001553512,0.00009246384,0.0006825136,0.00002474535,0.000008979231,0.00008359597,0.00004334636,0.00003798981,0.9979609,0.0001032038,0.00004873496,0.0007582291],"study_design_scores_gemma":[0.00003674878,0.00203736,0.03226858,0.00002726103,0.00003060337,0.0008658078,0.0002367419,0.0009873422,0.9621083,0.0001807587,0.001206975,0.00001354956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978479,0.0004081787,0.0006831399,0.00005457148,0.0000163527,0.00001329207,0.0001887661,0.00004879841,0.0007390238],"genre_scores_gemma":[0.9971103,0.000261232,0.0007544462,0.0000666691,0.000005465429,0.00003198638,0.0003199619,0.00002409704,0.001425943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001258115,"threshold_uncertainty_score":0.004208803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008581504925269457,"score_gpt":0.2516961923749056,"score_spread":0.2431146874496362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}