{"id":"W1975485903","doi":"10.1016/j.freeradbiomed.2010.03.025","title":"Oxidatively generated base damage to cellular DNA","year":2010,"lang":"en","type":"review","venue":"Free Radical Biology and Medicine","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":524,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Nucleobase; DNA damage; Chemistry; Singlet oxygen; DNA; Reactive oxygen species; Deoxyribose; DNA oxidation; Biophysics; Oxidative stress; Hydroxyl radical; Photochemistry; Oxygen; Biochemistry; Radical; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005883831,0.0005160916,0.001301756,0.0001544762,0.0001043403,0.000006776758,0.0005791635,0.001484255,0.0002038338],"category_scores_gemma":[0.00112776,0.0003521644,0.000165895,0.000187809,0.0006589614,0.000001792706,0.0004040012,0.0006022849,0.0000429048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001430796,"about_ca_system_score_gemma":0.0001847243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001551971,"about_ca_topic_score_gemma":0.00002082824,"domain_scores_codex":[0.9976713,0.0003466234,0.0005144604,0.0009147269,0.0001119395,0.0004409218],"domain_scores_gemma":[0.9982723,0.00007484471,0.0001763932,0.0008916028,0.00006202579,0.0005228075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003906549,0.00006595571,0.00000590325,0.0009227972,0.0002291253,0.00007237964,0.00001827919,2.788019e-8,0.4447212,0.001691388,0.02060092,0.531633],"study_design_scores_gemma":[0.0005866452,0.0009837559,0.000002401562,0.0007063092,0.0003234367,0.00007554603,0.000004631684,0.000001845218,0.01227146,0.0001889908,0.9844825,0.000372428],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002489713,0.9933181,0.00143578,0.0004748769,0.0007985088,0.0006804742,0.0001861117,0.00003802319,0.0005784552],"genre_scores_gemma":[0.0001221726,0.9912996,0.001786476,0.001098906,0.001846989,0.0001038543,0.002498296,0.00006062352,0.001183035],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9638816,"threshold_uncertainty_score":0.999893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02433888684971687,"score_gpt":0.3131143751325124,"score_spread":0.2887754882827956,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}