{"id":"W1975519565","doi":"10.1016/j.ahj.2008.07.026","title":"Design and rationale of CURRENT-OASIS 7: A randomized, 2 × 2 factorial trial evaluating optimal dosing strategies for clopidogrel and aspirin in patients with ST and non–ST-elevation acute coronary syndromes managed with an early invasive strategy","year":2008,"lang":"en","type":"article","venue":"American Heart Journal","topic":"Antiplatelet Therapy and Cardiovascular Diseases","field":"Medicine","cited_by":153,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hamilton Health Sciences; McMaster University; Population Health Research Institute","funders":"","keywords":"Medicine; Clopidogrel; Regimen; Loading dose; Maintenance dose; Aspirin; Dosing; Acute coronary syndrome; Randomized controlled trial; Internal medicine; Myocardial infarction; Cardiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005622518,0.0001753374,0.0007200115,0.0001441402,0.0001937431,0.00006415763,0.00003009333,0.00003211639,0.000005050913],"category_scores_gemma":[0.00004852693,0.0001255563,0.00007787307,0.0001300611,0.0004673003,0.0004904285,0.00001061922,0.0001722611,4.724798e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000245472,"about_ca_system_score_gemma":0.000437036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004014991,"about_ca_topic_score_gemma":0.000005653259,"domain_scores_codex":[0.998493,0.0003677001,0.0003430001,0.0002255825,0.0003888316,0.0001819324],"domain_scores_gemma":[0.9989775,0.0003313757,0.0002694517,0.00008176673,0.0002080381,0.0001318552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7423014,0.0002708004,0.2320155,0.00007716574,0.001290229,0.00005213378,0.001216676,0.0006862304,0.0001848762,0.00001082335,0.000009168758,0.02188493],"study_design_scores_gemma":[0.4771498,0.02280255,0.4951509,0.0003470496,0.0009900004,0.0005728917,0.001420574,0.001158648,0.0000488424,0.0001018003,0.000003293241,0.0002536875],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875987,0.0004921643,0.009967221,0.00001777898,0.00004251905,0.001855488,0.00001777932,0.000007036628,0.000001323875],"genre_scores_gemma":[0.9919388,0.0004723284,0.007351344,0.0000199402,0.0001071583,0.00005096351,0.00003866338,0.00001923485,0.00000152914],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2651516,"threshold_uncertainty_score":0.5120035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05144754786856204,"score_gpt":0.3189265567882665,"score_spread":0.2674790089197045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}