{"id":"W1975574832","doi":"10.1002/cbic.200900202","title":"STD‐NMR Studies Suggest that Two Acceptor Substrates for GlfT2, a Bifunctional Galactofuranosyltransferase Required for the Biosynthesis of <i>Mycobacterium tuberculosis</i> Arabinogalactan, Compete for the Same Binding Site","year":2009,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Stereochemistry; Galactan; Bifunctional; Moiety; Peptidoglycan; Active site; Arabinogalactan; Trisaccharide; Nuclear magnetic resonance spectroscopy; Enzyme; Biochemistry; Polysaccharide; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000242053,0.0007297874,0.000372349,0.00008868241,0.0001932038,0.0002822458,0.000431857,0.0004784147,0.001500929],"category_scores_gemma":[0.0003872173,0.0001670985,0.0002165804,0.000139371,0.0002970916,0.0002835871,0.0001780773,0.0008462197,0.0005166617],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002761089,"about_ca_system_score_gemma":0.0001618114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005849964,"about_ca_topic_score_gemma":0.0006052127,"domain_scores_codex":[0.99988,0.00002372815,0.000006399142,0.00002668716,0.00003333942,0.00002982948],"domain_scores_gemma":[0.9997161,0.0001092553,0.00005611439,0.00002060865,0.0000451279,0.00005269706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001696368,0.00002571019,0.0001741449,0.00003385367,0.000006861129,0.00004673343,0.00002448684,0.0001177363,0.9981568,0.00006342528,0.00003680589,0.001143617],"study_design_scores_gemma":[0.00001037284,0.0001402498,0.0007191685,0.000002245434,0.000006666751,0.0001142824,0.00001413808,0.0009523007,0.9975075,0.00003261678,0.0004945349,0.000005909507],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9779626,0.001396891,0.01657514,0.0001922669,0.00007264376,0.00004828695,0.0003293135,0.0001929265,0.003230015],"genre_scores_gemma":[0.9860008,0.0006857529,0.01001579,0.0001621866,0.00002911617,0.00004398134,0.0008480469,0.00003937916,0.002174979],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001500929,"threshold_uncertainty_score":0.005021155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04120293558580649,"score_gpt":0.278559206597536,"score_spread":0.2373562710117295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}