{"id":"W1975574832","doi":"10.1002/cbic.200900202","title":"STD‐NMR Studies Suggest that Two Acceptor Substrates for GlfT2, a Bifunctional Galactofuranosyltransferase Required for the Biosynthesis of <i>Mycobacterium tuberculosis</i> Arabinogalactan, Compete for the Same Binding Site","year":2009,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Stereochemistry; Galactan; Bifunctional; Moiety; Peptidoglycan; Active site; Arabinogalactan; Trisaccharide; Nuclear magnetic resonance spectroscopy; Enzyme; Biochemistry; Polysaccharide; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005828758,0.000665241,0.0008375795,0.0000617663,0.0007204732,0.0001621414,0.0006951991,0.0002881339,0.0002251258],"category_scores_gemma":[0.000720804,0.000454178,0.001067139,0.000260616,0.0004292577,0.0002151629,0.0000514916,0.0002224171,0.00000489172],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001802523,"about_ca_system_score_gemma":0.0001212368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001359692,"about_ca_topic_score_gemma":0.00002005597,"domain_scores_codex":[0.9972776,0.00002270784,0.0007571925,0.0007826724,0.0003805762,0.000779205],"domain_scores_gemma":[0.9914706,0.006644804,0.0003818564,0.0008738264,0.0004848317,0.000144034],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001184457,0.0002080411,0.0005463297,0.0009544254,0.0009522854,8.425446e-7,0.0004516516,0.00001884542,0.9919133,0.00008343474,0.002511051,0.001175304],"study_design_scores_gemma":[0.002099816,0.00008260125,0.0002412742,0.0002131408,0.001057957,0.00001330113,0.002011176,0.000377121,0.9892335,0.0001772123,0.003939525,0.0005533622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868007,0.003337262,0.0003709691,0.004262904,0.0003151011,0.001165789,0.003300862,0.0001430443,0.0003033565],"genre_scores_gemma":[0.9956221,0.0007501128,0.0003753077,0.0002392679,0.00084515,0.0009524695,0.0004856235,0.00008292471,0.0006470294],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008821402,"threshold_uncertainty_score":0.999791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04120293558580649,"score_gpt":0.278559206597536,"score_spread":0.2373562710117295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}