{"id":"W1975624043","doi":"10.1016/j.jhep.2012.01.017","title":"Mechanistic biomarkers in acute liver injury: Are we there yet?","year":2012,"lang":"en","type":"letter","venue":"Journal of Hepatology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":22,"is_retracted":true,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Liver transplantation; Intensive care medicine; Liver failure; Transplantation; Liver disease; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03496553,0.001638755,0.00344074,0.002425923,0.001943401,0.009698455,0.005335112,0.01400437,0.01384856],"category_scores_gemma":[0.1126927,0.0009634551,0.002196045,0.002824501,0.005397853,0.01276399,0.002692102,0.01411018,0.01383042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001725757,"about_ca_system_score_gemma":0.006130641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003015799,"about_ca_topic_score_gemma":0.003938994,"domain_scores_codex":[0.9907801,0.002918126,0.00259129,0.0006652334,0.002437451,0.0006077875],"domain_scores_gemma":[0.8709407,0.03714015,0.007551709,0.008330827,0.06868719,0.00734942],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004647967,0.0001178681,0.002967085,0.002320179,0.0001689305,0.001057391,0.0005903555,0.00007565675,0.0009735897,0.002908835,0.7953927,0.1929627],"study_design_scores_gemma":[0.0001541278,0.0003301307,0.006305315,0.005162614,0.000281709,0.002795532,0.001952871,0.0003681098,0.001179655,0.01001396,0.9712458,0.0002101585],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001797847,0.1663367,0.001642975,0.4899692,0.3372777,0.00006956484,0.0004026515,0.0003350575,0.002168363],"genre_scores_gemma":[0.01981216,0.1814664,0.008116323,0.2679868,0.495355,0.0002209807,0.0008289713,0.0006825224,0.02553095],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03496553,"threshold_uncertainty_score":0.1849176,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1436352127210928,"score_gpt":0.4102834982551052,"score_spread":0.2666482855340123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}