{"id":"W1975643185","doi":"10.1038/nature13804","title":"Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells","year":2014,"lang":"en","type":"article","venue":"Nature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":464,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Embryonic stem cell; Biology; Induced pluripotent stem cell; Stem cell; Cell biology; Retrovirus; Transcription factor; Endogenous retrovirus; Genetics; Cell culture; Gene; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008763205,0.0001701054,0.0001338458,0.00003787872,0.00006398361,0.00002545301,0.0001784167,0.0007869143,0.00001563463],"category_scores_gemma":[0.000005045691,0.0001619356,0.0001012989,0.00007153706,0.00002492152,0.00000277448,0.00003038822,0.0004644599,0.00002461108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001358853,"about_ca_system_score_gemma":0.00001366322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002292442,"about_ca_topic_score_gemma":0.000007139854,"domain_scores_codex":[0.9991321,0.00002984088,0.0001399396,0.0003223541,0.0001369855,0.0002387921],"domain_scores_gemma":[0.9995067,0.000007616622,0.00003517495,0.0003243361,0.00005711473,0.00006903302],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003222322,0.0000194561,0.0001653461,0.00002924421,0.00001739362,0.000002074706,0.00004958267,0.0005292756,0.9902313,0.0001277876,0.00405682,0.004739513],"study_design_scores_gemma":[0.0002772597,0.0001091959,0.000308749,0.000008116252,0.00001070699,0.00001391663,0.0000182887,0.00008737205,0.6764181,0.00001084139,0.3225834,0.0001540323],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9621863,0.01440983,0.017959,0.0001347273,0.001653332,0.0002903829,0.00004979745,0.00008165807,0.003234921],"genre_scores_gemma":[0.9969137,0.0006116735,0.001131143,0.000332301,0.0004216989,0.000009466657,0.00006996419,0.00003290567,0.000477184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3185266,"threshold_uncertainty_score":0.6603541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009989408700281237,"score_gpt":0.2435276358812255,"score_spread":0.2335382271809443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}