{"id":"W1975668759","doi":"10.1002/ijc.1031","title":"Evaluation of cell survival, DNA double strand breaks, and DNA synthesis during concurrent camptothecin and X‐radiation treatments","year":2001,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Regional Cancer Foundation","funders":"","keywords":"Camptothecin; DNA; Radioresistance; Clonogenic assay; DNA synthesis; Molecular biology; Biology; Radiosensitivity; Topoisomerase; DNA damage; Cell culture; Genetics; Biochemistry; Radiation therapy; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002806775,0.0004086387,0.000436309,0.0002148027,0.0001929138,0.000238681,0.0001891396,0.000276623,0.001216769],"category_scores_gemma":[0.0003243057,0.0001393571,0.0002138129,0.0002807217,0.0002209168,0.000232122,0.0001561289,0.0005152465,0.0002696555],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003025029,"about_ca_system_score_gemma":0.0003158748,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001288118,"about_ca_topic_score_gemma":0.001945738,"domain_scores_codex":[0.9997504,0.00005032495,0.0000176351,0.00005684173,0.00008757971,0.00003718721],"domain_scores_gemma":[0.9996619,0.000109916,0.00005347034,0.00003450767,0.0000912255,0.00004891558],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002408573,0.00005008877,0.00051237,0.00004486779,0.000007355264,0.00002666499,0.00004431867,0.0001139168,0.9973055,0.00002307429,0.00001492253,0.001616014],"study_design_scores_gemma":[0.00001038969,0.001216708,0.007045696,0.000004444612,0.00001496904,0.00006946121,0.00003641755,0.0005192541,0.9903153,0.00001626747,0.0007470601,0.000004015521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916489,0.003143675,0.003459945,0.00003411401,0.00002313338,0.00008695563,0.0004689404,0.00004534651,0.00108898],"genre_scores_gemma":[0.9868562,0.001867112,0.005990352,0.00004104415,0.00001506081,0.0001675012,0.0009145768,0.00002944089,0.004118792],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001288118,"threshold_uncertainty_score":0.00407052,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02482227500277646,"score_gpt":0.3280133798437708,"score_spread":0.3031911048409944,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}