{"id":"W1975668759","doi":"10.1002/ijc.1031","title":"Evaluation of cell survival, DNA double strand breaks, and DNA synthesis during concurrent camptothecin and X‐radiation treatments","year":2001,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Regional Cancer Foundation","funders":"","keywords":"Camptothecin; DNA; Radioresistance; Clonogenic assay; DNA synthesis; Molecular biology; Biology; Radiosensitivity; Topoisomerase; DNA damage; Cell culture; Genetics; Biochemistry; Radiation therapy; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002679281,0.0000728542,0.0001042078,0.00005434266,0.00002003673,0.00001967451,0.00006917329,0.00004052814,0.00006010873],"category_scores_gemma":[0.000009686019,0.00006436038,0.00004122491,0.00002036931,0.00002297962,0.00001065287,0.00001703051,0.0000309666,1.357127e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006564534,"about_ca_system_score_gemma":0.0001063819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006306062,"about_ca_topic_score_gemma":0.0001063654,"domain_scores_codex":[0.9992391,0.0000334282,0.0001986781,0.00009632693,0.000367473,0.00006493337],"domain_scores_gemma":[0.9992675,0.00001028809,0.0002316916,0.00004784528,0.0004004054,0.00004230392],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003843502,0.0000646589,0.003474023,0.000008022986,0.0004441732,0.000001819635,0.00009324939,0.0001471953,0.9130724,0.00003146088,0.00001562417,0.082263],"study_design_scores_gemma":[0.004248618,0.0001295458,0.01855605,0.00005565701,0.0002892603,0.00003601405,0.00005796932,0.0001086822,0.9738274,0.0001343626,0.002473025,0.00008341921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923599,0.00656525,0.0001867022,0.0001261587,0.0004799363,0.00007619598,0.0000317728,8.122809e-7,0.0001732424],"genre_scores_gemma":[0.9883957,0.01123182,0.00002194694,0.00001863917,0.000249032,0.000007904979,0.000004883122,0.000007695823,0.00006237182],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08217958,"threshold_uncertainty_score":0.262454,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02482227500277646,"score_gpt":0.3280133798437708,"score_spread":0.3031911048409944,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}