{"id":"W1975696612","doi":"10.1073/pnas.1010795108","title":"Spatial restriction of receptor tyrosine kinase activity through a polarized endocytic cycle controls border cell migration","year":2010,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Plant Reproductive Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Exocyst; Cell biology; Cell migration; Endocytic cycle; Biology; Endosome; Cell polarity; Endocytosis; Border cells; Receptor tyrosine kinase; Small GTPase; Exocytosis; Cell; Kinase; Signal transduction; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000572755,0.00008202431,0.0001333762,0.00005371367,0.00008388001,0.000006911332,0.0003167364,0.0001418468,0.000007289804],"category_scores_gemma":[0.0009587836,0.00005831631,0.00006239187,0.0002269145,0.0005631706,0.00003417611,0.00008091523,0.000137493,4.319401e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001049112,"about_ca_system_score_gemma":0.00006274308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008513875,"about_ca_topic_score_gemma":0.00000242554,"domain_scores_codex":[0.999047,0.0000136025,0.0002110412,0.0002701235,0.0003484913,0.0001097433],"domain_scores_gemma":[0.9991324,0.00003782538,0.0004815866,0.00001637118,0.0003142727,0.00001755981],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001437194,0.00007812376,0.005687333,0.00001574568,0.000009793039,1.380585e-9,0.00002192932,0.000007475124,0.9924576,0.001343398,0.0001191718,0.0001156856],"study_design_scores_gemma":[0.000331573,0.000136947,0.04101492,0.00000813157,0.000009846901,0.000003221092,0.00001697707,0.0001381165,0.9558977,0.001692971,0.0006927435,0.00005680073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997905,0.00006550267,0.00002310022,0.0009705044,0.00005849226,0.0001996434,0.00004878612,0.000003504408,0.0007254902],"genre_scores_gemma":[0.9980966,0.00004924488,0.00156553,0.0000494199,0.000170226,0.00000869071,0.000002386994,0.000003049907,0.00005486059],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03655988,"threshold_uncertainty_score":0.237807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01555591854169655,"score_gpt":0.2886240194316814,"score_spread":0.2730681008899849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}