{"id":"W1975698020","doi":"10.1139/o05-047","title":"Hypoxia inducible factor-1: regulation by nitric oxide in posthypoxic microvascular endothelium","year":2005,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Thomas F. and Kate Miller Jeffress Memorial Trust","keywords":"Nitric oxide synthase; Hypoxia (environmental); Nitric oxide; Small interfering RNA; Hypoxia-inducible factors; Biology; Cell biology; Endothelium; Transcription factor; Endothelial stem cell; Messenger RNA; Hypoxia-Inducible Factor 1; Molecular biology; Chemistry; Biochemistry; RNA; Endocrinology; Gene; Oxygen; In vitro","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001527536,0.0001843307,0.0001349935,0.000141568,0.0001502158,0.0001947121,0.0001957874,0.000250819,0.0005615296],"category_scores_gemma":[0.00009638885,0.00007506939,0.00009278946,0.000112231,0.0001521785,0.0002310916,0.0001205636,0.0002161703,0.0001425981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003507805,"about_ca_system_score_gemma":0.0001170678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006403399,"about_ca_topic_score_gemma":0.0007152897,"domain_scores_codex":[0.9999099,0.00001868319,0.000004446245,0.00001843701,0.00002287732,0.00002566051],"domain_scores_gemma":[0.9999304,0.000006527525,0.00002418142,0.000004161662,0.00001526821,0.00001945338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008484184,0.00001226595,0.0002281484,0.00004620819,0.000001610444,0.00008136393,0.00001466992,0.00002857565,0.9972267,0.0001788049,0.00006220988,0.002034464],"study_design_scores_gemma":[0.00002713379,0.0004751923,0.06534591,0.00001940382,0.00001934908,0.0008965207,0.0000478657,0.001244044,0.9233486,0.0004580648,0.008107551,0.00001031172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9647981,0.02532339,0.006714727,0.0004252392,0.00007459732,0.0000435295,0.0002796201,0.0001022213,0.002238535],"genre_scores_gemma":[0.9875001,0.005569704,0.002664951,0.0001205423,0.00007899992,0.00006339146,0.0003548446,0.00001155793,0.003635931],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006403399,"threshold_uncertainty_score":0.002545059,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005971243121907199,"score_gpt":0.2120010953698225,"score_spread":0.2060298522479153,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}