{"id":"W1975719291","doi":"10.1371/journal.pone.0051400","title":"Adeno-Associated Virus Vector Mediated Expression of an Oncogenic Retroviral Envelope Protein Induces Lung Adenocarcinomas in Immunocompetent Mice","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Cancer Research Society","keywords":"Lung cancer; Cancer research; Biology; Adenocarcinoma; Immune system; Immunology; Tumor progression; Cancer; Virology; Medicine; Pathology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007580193,0.0009954879,0.0005070744,0.001606527,0.000423598,0.0006876264,0.0007125356,0.001083107,0.003451027],"category_scores_gemma":[0.0002649629,0.0006211737,0.0008010906,0.0004850696,0.0006800719,0.0006046175,0.0004450376,0.002728912,0.001152783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004259571,"about_ca_system_score_gemma":0.0003697091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005364443,"about_ca_topic_score_gemma":0.0009584611,"domain_scores_codex":[0.9990948,0.0001247471,0.0001508991,0.0002385229,0.0002122955,0.0001788039],"domain_scores_gemma":[0.999216,0.0001352415,0.0002312713,0.0001331162,0.00004654182,0.0002377134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002320482,0.0003035188,0.0001611927,0.00003603702,0.000008897681,0.0001264234,0.00005232826,0.00006565731,0.9979042,0.0002647206,0.00007489596,0.0007700886],"study_design_scores_gemma":[0.0001235917,0.00186161,0.003096428,0.00002664331,0.00003189674,0.0007068269,0.000062058,0.001268202,0.988785,0.0001385012,0.003886112,0.00001299623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9733009,0.001586591,0.01461314,0.0003806232,0.0002333676,0.0005507363,0.002890884,0.000786967,0.005656852],"genre_scores_gemma":[0.9574842,0.002038663,0.01531989,0.0002869266,0.00006981933,0.0007995311,0.003662457,0.0002439315,0.02009455],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003451027,"threshold_uncertainty_score":0.01154482,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03275370887899209,"score_gpt":0.2666970467502932,"score_spread":0.2339433378713011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}