{"id":"W1975869283","doi":"10.1038/icb.2014.96","title":"Lymphocyte repertoire selection and intracellular self/non‐self‐discrimination: historical overview","year":2014,"lang":"en","type":"review","venue":"Immunology and Cell Biology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Queen's University","keywords":"Intracellular; Extracellular; Biology; Major histocompatibility complex; Negative selection; Receptor; Cell biology; Genetics; Immune system; Genome; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008673994,0.001046554,0.001240928,0.003227092,0.0004010155,0.001467826,0.001165606,0.00165671,0.003991139],"category_scores_gemma":[0.0009706749,0.0003891944,0.0003657816,0.0030428,0.001220197,0.002589721,0.001055668,0.00208073,0.003011871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001297062,"about_ca_system_score_gemma":0.0012453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001156297,"about_ca_topic_score_gemma":0.0009780681,"domain_scores_codex":[0.999795,0.00003919631,0.00002887444,0.00005234707,0.00005869212,0.00002602977],"domain_scores_gemma":[0.9995291,0.0002152777,0.00005561794,0.00001619603,0.0001145782,0.00006920194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001166515,0.00007919841,0.0004499708,0.01131995,0.0000544305,0.0003996021,0.0001357017,0.0004004105,0.001055244,0.01161371,0.03972355,0.9346516],"study_design_scores_gemma":[0.000007242737,0.0000567425,0.0007459248,0.001935509,0.00003332921,0.001451184,0.00005535759,0.00005605838,0.0002010204,0.002968942,0.9924725,0.00001614332],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008684333,0.9978207,0.0001548745,0.0003509614,0.0003302659,0.000003238687,0.00001204427,0.000006190751,0.001234777],"genre_scores_gemma":[0.000915352,0.9970667,0.0001912243,0.0003368873,0.0007316729,0.000008086076,0.00002689479,0.000002461391,0.0007207691],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003991139,"threshold_uncertainty_score":0.01335168,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01645069360988664,"score_gpt":0.2470291698677095,"score_spread":0.2305784762578229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}