{"id":"W1975869283","doi":"10.1038/icb.2014.96","title":"Lymphocyte repertoire selection and intracellular self/non‐self‐discrimination: historical overview","year":2014,"lang":"en","type":"review","venue":"Immunology and Cell Biology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Queen's University","keywords":"Intracellular; Extracellular; Biology; Major histocompatibility complex; Negative selection; Receptor; Cell biology; Genetics; Immune system; Genome; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007119901,0.001272388,0.003723945,0.0006149351,0.0008447112,0.00003794144,0.0006740707,0.004936558,0.0004032608],"category_scores_gemma":[0.0000777249,0.001058197,0.0005100608,0.0003787419,0.0007828531,0.0001219974,0.0006291043,0.001898546,0.0007955506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000657235,"about_ca_system_score_gemma":0.0004039125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002443147,"about_ca_topic_score_gemma":0.00003030342,"domain_scores_codex":[0.9933395,0.002101028,0.001519925,0.001774403,0.00004632349,0.001218837],"domain_scores_gemma":[0.9972146,0.0007225355,0.001002515,0.0008346249,0.0001430722,0.00008271556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001304181,0.0006544639,0.0000604279,0.00661606,0.002238097,0.00003755023,0.0004009048,1.081919e-7,0.08845445,0.003074619,0.00161307,0.8967198],"study_design_scores_gemma":[0.001840298,0.001152746,0.00001207541,0.000687296,0.001824775,0.002198018,0.00003681713,0.000004193269,0.00317094,0.0002113282,0.9878165,0.001045069],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002243254,0.9919045,0.00007194212,0.0001397893,0.003221613,0.000867893,0.00002517464,0.0004028171,0.001123045],"genre_scores_gemma":[0.003196215,0.9894273,0.0002007827,0.0001516253,0.0002019451,0.0002567232,0.0006821647,0.0001083231,0.005774973],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9862034,"threshold_uncertainty_score":0.9999824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01645069360988664,"score_gpt":0.2470291698677095,"score_spread":0.2305784762578229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}