{"id":"W1975881580","doi":"10.1124/mol.63.1.136","title":"Activation of Microsomal Glutathione S-Transferase by Peroxynitrite","year":2003,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Glutathione Transferases and Polymorphisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"","keywords":"Tetranitromethane; Peroxynitrite; Chemistry; Biochemistry; Microsome; Glutathione; Enzyme; Dithiothreitol; Tyrosine; Lipid peroxidation; Enzyme assay; Nitration; Superoxide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004592617,0.0003839669,0.0003534873,0.0004047004,0.0002094035,0.0002884444,0.0002318955,0.000328892,0.002300041],"category_scores_gemma":[0.0006007141,0.0002517536,0.0002806816,0.0002703706,0.0002590352,0.0002445224,0.0002563692,0.0006786492,0.0002496568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003107876,"about_ca_system_score_gemma":0.0002878576,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00110061,"about_ca_topic_score_gemma":0.0006341164,"domain_scores_codex":[0.9996669,0.0001826963,0.00002003086,0.00005712554,0.00003578263,0.00003748679],"domain_scores_gemma":[0.9996675,0.00007448206,0.00008363349,0.00006709906,0.0000419163,0.00006533141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005102231,0.0003018858,0.03299425,0.00007210916,0.0001969456,0.0004962212,0.0001013911,0.0001825395,0.9505349,0.001534974,0.0002045421,0.008278008],"study_design_scores_gemma":[0.0001733283,0.00181454,0.1333195,0.00001826194,0.0002651066,0.002294659,0.000126172,0.001799613,0.8570952,0.001125467,0.001946155,0.0000219329],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960758,0.0004696989,0.002383211,0.0001668974,0.00002162984,0.00001925297,0.000137888,0.00004040034,0.0006851773],"genre_scores_gemma":[0.9974084,0.0002537327,0.0007766575,0.00002922589,0.000008386298,0.00001858207,0.0001502216,0.00001206087,0.001342635],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002300041,"threshold_uncertainty_score":0.007694423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004885039762210564,"score_gpt":0.2427577479266701,"score_spread":0.2378727081644596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}