{"id":"W1976019172","doi":"10.1056/nejm200208223470816","title":"Sulindac in Familial Adenomatous Polyposis","year":2002,"lang":"en","type":"letter","venue":"New England Journal of Medicine","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Sulindac; Familial adenomatous polyposis; Adenomatous polyposis coli; Medicine; Colorectal cancer; Mutation; Gastroenterology; Gene; Cancer research; Gene mutation; Allele; Internal medicine; Cancer; Genetics; Biology; Nonsteroidal","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008242433,0.0009214042,0.001287725,0.0007224376,0.001231989,0.0008157157,0.001029022,0.01288734,0.00248253],"category_scores_gemma":[0.004536924,0.0003793415,0.0008536287,0.0006051746,0.0009252072,0.0009677933,0.0003386361,0.005992844,0.001446862],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001518609,"about_ca_system_score_gemma":0.0005684149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001390856,"about_ca_topic_score_gemma":0.002939246,"domain_scores_codex":[0.999424,0.0001654283,0.00008587664,0.00009834526,0.000114497,0.00011189],"domain_scores_gemma":[0.9984998,0.0008930988,0.0001230889,0.0000483546,0.0001603264,0.000275354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008816872,0.000168275,0.006768049,0.0004149625,0.0001187701,0.7875842,0.0001962394,0.0004773448,0.001735625,0.001608115,0.17172,0.0283267],"study_design_scores_gemma":[0.0008688819,0.0009248494,0.01345663,0.0004418861,0.0003612748,0.7281057,0.0003781456,0.003381253,0.002786866,0.005096072,0.2440844,0.0001139309],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.07236888,0.03257051,0.001448838,0.8107911,0.05820045,0.0001436078,0.0003182004,0.0002698763,0.02388855],"genre_scores_gemma":[0.3863066,0.01613265,0.001739085,0.4174902,0.1476054,0.0001160821,0.000250892,0.00009191965,0.03026721],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01288734,"threshold_uncertainty_score":0.01101834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02986259270189602,"score_gpt":0.2706504530579109,"score_spread":0.2407878603560149,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}