{"id":"W1976030524","doi":"10.1097/00005768-200305001-00675","title":"THE POTENTIAL OF CONTRACTILE ACTIVITY TO REVERSE THE SEVERITY OF MTDNA DEFECTS","year":2003,"lang":"en","type":"article","venue":"Medicine & Science in Sports & Exercise","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; York University","funders":"","keywords":"Mitochondrial biogenesis; TFAM; Mitochondrial DNA; Biology; Cell biology; Mitochondrion; Myocyte; Internal medicine; Molecular biology; Biochemistry; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001589702,0.0003001456,0.0001909772,0.00011456,0.0001095446,0.0002011056,0.0002202701,0.0003505587,0.001221853],"category_scores_gemma":[0.000206911,0.00007274791,0.000207588,0.00006281949,0.0001641294,0.0001504225,0.0001939065,0.0004798515,0.000202068],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001042603,"about_ca_system_score_gemma":0.0001211296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002549461,"about_ca_topic_score_gemma":0.0005245648,"domain_scores_codex":[0.9999329,0.00001585706,0.000005661353,0.00001228667,0.00001028175,0.00002305513],"domain_scores_gemma":[0.9998724,0.00001954621,0.00003115739,0.00001518626,0.00001760487,0.00004409227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004605753,0.0001039423,0.0002894683,0.00007178302,0.00001233347,0.00004500102,0.00001181649,0.00003686467,0.9941596,0.00006029645,0.00008012007,0.004668254],"study_design_scores_gemma":[0.0001781463,0.01089018,0.04925736,0.0000682347,0.0001235489,0.0007583615,0.0001448039,0.001578427,0.9306749,0.0001378552,0.006173279,0.00001491138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941986,0.002923837,0.001294745,0.0002507235,0.00006836558,0.00003499883,0.0001492782,0.00005528125,0.001024221],"genre_scores_gemma":[0.9942736,0.001948642,0.00132934,0.0001213375,0.0000418401,0.00005954951,0.0003729765,0.00001474375,0.001837985],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001221853,"threshold_uncertainty_score":0.004087567,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00860794475776745,"score_gpt":0.2591953601114924,"score_spread":0.250587415353725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}