{"id":"W1976059236","doi":"10.1016/j.febslet.2010.10.010","title":"The space and time frames of T cell activation at the immunological synapse","year":2010,"lang":"en","type":"article","venue":"FEBS Letters","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Immunological synapse; T-cell receptor; T cell; Antigen; Cell biology; MHC restriction; Stimulation; Biology; Neuroscience; Immunology; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002460234,0.0001502823,0.0001782162,0.00003200992,0.0004930429,0.00001745839,0.0003146582,0.0002724892,0.0004981074],"category_scores_gemma":[0.00008513456,0.00007823889,0.00007011295,0.00007081265,0.001330635,0.00004785484,0.0002168393,0.000622132,0.0004976144],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001388471,"about_ca_system_score_gemma":0.00001363334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006608514,"about_ca_topic_score_gemma":0.00001211661,"domain_scores_codex":[0.9990641,0.0002003386,0.000192238,0.0002106552,0.00003082818,0.0003018808],"domain_scores_gemma":[0.9986599,0.0007372961,0.000155583,0.000409848,0.00002791518,0.000009466388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001425438,0.00003881801,0.0004023715,0.00000374341,0.00007215868,0.000001158151,0.00021323,7.569862e-7,0.9858823,0.0006273333,0.01166468,0.0009509269],"study_design_scores_gemma":[0.0004757199,0.00009184768,0.003300722,0.000004773009,0.00002156995,0.00003994826,0.0001100014,0.000001470527,0.8935894,0.00009453612,0.1021702,0.00009983483],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9814183,0.001211293,0.00001657605,0.01562258,0.0006164089,0.0001778587,0.000006391916,0.00003640265,0.0008941723],"genre_scores_gemma":[0.9928647,0.0001330387,0.00002993245,0.0009421975,0.00003065595,0.0000151441,0.00002258061,0.00001063022,0.00595116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09229291,"threshold_uncertainty_score":0.6395992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004881661706594547,"score_gpt":0.1890845179934328,"score_spread":0.1842028562868383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}