{"id":"W1976081765","doi":"10.1007/s00520-011-1235-4","title":"Single-dose intravenous casopitant in combination with ondansetron and dexamethasone for the prevention of oxaliplatin-induced nausea and vomiting: a multicenter, randomized, double-blind, active-controlled, two arm, parallel group study","year":2011,"lang":"en","type":"article","venue":"Supportive Care in Cancer","topic":"Nausea and vomiting management","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Medicine; Ondansetron; Oxaliplatin; Antiemetic; Retching; Placebo; Vomiting; Nausea; Anesthesia; Dexamethasone; Clinical endpoint; Chemotherapy-induced nausea and vomiting; Internal medicine; Randomized controlled trial; Colorectal cancer; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00103632,0.0002291544,0.0008447534,0.0002366353,0.00006200087,0.00001938884,0.00006596544,0.00006094308,0.0000180173],"category_scores_gemma":[0.0002003835,0.0001531475,0.00008208265,0.0001857062,0.0001394981,0.0001400689,0.00004569145,0.0002113458,1.244032e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002399473,"about_ca_system_score_gemma":0.00009800652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00247876,"about_ca_topic_score_gemma":0.01176298,"domain_scores_codex":[0.9982342,0.0002376817,0.000611947,0.0003952465,0.0002451949,0.0002757453],"domain_scores_gemma":[0.9984301,0.0005957407,0.0004658802,0.0001807842,0.00026465,0.00006286922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8366535,0.00277508,0.1024274,0.0003848255,0.0007366344,0.00004965291,0.03197387,0.00001130523,0.0009292783,0.0003145483,0.00000199421,0.0237419],"study_design_scores_gemma":[0.8856739,0.005385417,0.07738325,0.0005458671,0.0009959454,0.000006144397,0.02695611,0.0005131091,0.002203937,0.000134156,0.000006489696,0.0001956883],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864057,0.0006796313,0.0005117739,0.0001302018,0.0001027209,0.01197957,0.00001268636,0.00001399239,0.0001636873],"genre_scores_gemma":[0.9965932,0.0001283672,0.0007623367,0.0000376826,0.00003614605,0.002360495,0.00002109129,0.000029059,0.0000316351],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04902041,"threshold_uncertainty_score":0.6564017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07091560206910563,"score_gpt":0.3472981242811364,"score_spread":0.2763825222120308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}