{"id":"W1976081765","doi":"10.1007/s00520-011-1235-4","title":"Single-dose intravenous casopitant in combination with ondansetron and dexamethasone for the prevention of oxaliplatin-induced nausea and vomiting: a multicenter, randomized, double-blind, active-controlled, two arm, parallel group study","year":2011,"lang":"en","type":"article","venue":"Supportive Care in Cancer","topic":"Nausea and vomiting management","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Medicine; Ondansetron; Oxaliplatin; Antiemetic; Retching; Placebo; Vomiting; Nausea; Anesthesia; Dexamethasone; Clinical endpoint; Chemotherapy-induced nausea and vomiting; Internal medicine; Randomized controlled trial; Colorectal cancer; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001740908,0.001893598,0.006104368,0.001167432,0.0008722437,0.001333583,0.001996078,0.002043484,0.003789254],"category_scores_gemma":[0.002018189,0.001245805,0.00185236,0.001151243,0.002749936,0.001962621,0.0005722899,0.003509452,0.0007910975],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009109132,"about_ca_system_score_gemma":0.002515969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001579408,"about_ca_topic_score_gemma":0.002287474,"domain_scores_codex":[0.998896,0.0004667053,0.0001024487,0.0002058675,0.0001254487,0.0002034252],"domain_scores_gemma":[0.9985682,0.0003106891,0.0002309202,0.0001809025,0.00009873843,0.00061061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9511034,0.03173162,0.000385436,0.0003376976,0.0006476714,0.0000327142,0.00005175696,0.0002061203,0.003870103,0.0000773319,0.0002534662,0.01130263],"study_design_scores_gemma":[0.8675487,0.1302504,0.000855406,0.00001158729,0.0002820594,0.00001830943,0.00001997542,0.0002399116,0.0005546711,0.00004072743,0.000163657,0.00001454976],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943997,0.001516847,0.0004641046,0.0002203831,0.0003301714,0.002110842,0.0002912424,0.0000742738,0.0005924304],"genre_scores_gemma":[0.990029,0.002482357,0.001939256,0.0004366042,0.0006249491,0.002382408,0.0005269612,0.00003191234,0.001546677],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006104368,"threshold_uncertainty_score":0.0126763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07091560206910563,"score_gpt":0.3472981242811364,"score_spread":0.2763825222120308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}