{"id":"W1976120640","doi":"10.1158/1538-7445.fbcr13-a45","title":"Abstract A45: Investigating the role of ASCL1 in regulating differentiation of gliobastoma precursor cells","year":2013,"lang":"en","type":"article","venue":"Cancer Research","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Biology; Neurogenesis; Phenotype; Cellular differentiation; Lineage markers; Wnt signaling pathway; Cancer research; Precursor cell; DKK1; Cell biology; Pathology; Cell; Genetics; Signal transduction; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001489406,0.0002076462,0.0001673517,0.0002280044,0.0001989354,0.0003445062,0.0001558016,0.0002439896,0.001780835],"category_scores_gemma":[0.00009578448,0.00008302158,0.0002090857,0.0002344095,0.0001655948,0.0002139451,0.0001503366,0.0004231363,0.0006153384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004022648,"about_ca_system_score_gemma":0.0002655086,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007322051,"about_ca_topic_score_gemma":0.0007904721,"domain_scores_codex":[0.9998955,0.00001447473,0.00001058218,0.00002422651,0.00003221666,0.00002302131],"domain_scores_gemma":[0.9999259,0.00001155656,0.00001681046,0.00000544985,0.00001282967,0.00002743145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001279928,0.0000230269,0.0003533389,0.00004921151,0.000002579431,0.00003697333,0.00001331346,0.00005473243,0.9979984,0.00005001785,0.00003779454,0.001252519],"study_design_scores_gemma":[0.00001526318,0.0004147118,0.01059062,0.000006656084,0.00001258538,0.000146746,0.00003778034,0.0008544773,0.9849998,0.00004796706,0.002870259,0.000003197281],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923726,0.002291377,0.002343032,0.0001291444,0.00002923477,0.00005150487,0.001013979,0.00006995782,0.001699098],"genre_scores_gemma":[0.9925395,0.001053683,0.002205239,0.00006775569,0.000009006839,0.00004650944,0.001167875,0.00001512284,0.002895448],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001780835,"threshold_uncertainty_score":0.005957484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02246850376717274,"score_gpt":0.3142680889758184,"score_spread":0.2917995852086457,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}