{"id":"W1976136773","doi":"10.1074/jbc.m102815200","title":"Reducing the Environmental Sensitivity of Yellow Fluorescent Protein","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Advanced Fluorescence Microscopy Techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1038,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; National Cancer Institute; Canadian Institutes of Health Research; University of California, San Diego; Howard Hughes Medical Institute","keywords":"Fluorescence; Sensitivity (control systems); Chemistry; Fluorescent protein; Green fluorescent protein; Biochemistry; Physics; Engineering","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003428053,0.0004184236,0.0003597629,0.0001092474,0.0001798959,0.0004481896,0.0003773703,0.0005883485,0.001333641],"category_scores_gemma":[0.0007480251,0.000194417,0.0002537857,0.0001396449,0.0003689356,0.0003919396,0.0007095778,0.0006224019,0.0006776239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003559393,"about_ca_system_score_gemma":0.0002453461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004754229,"about_ca_topic_score_gemma":0.0006052436,"domain_scores_codex":[0.9996287,0.0000726983,0.00002976737,0.00008478285,0.0001365237,0.00004752196],"domain_scores_gemma":[0.9995083,0.0001341803,0.000100326,0.00008340425,0.0001191519,0.00005468741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002454561,0.000006469335,0.0001205688,0.00003112334,0.000003054333,0.00003414484,0.0000119642,0.00007152189,0.9982369,0.000151961,0.00003850138,0.00126922],"study_design_scores_gemma":[0.000002449216,0.00002914663,0.0006326557,0.000002958365,0.000003248682,0.0002005406,0.000008663383,0.000389853,0.9957949,0.00006045707,0.002871877,0.000003311215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9409136,0.002934421,0.04983199,0.0005195053,0.00008257855,0.00005594044,0.0003280057,0.0007329246,0.004601044],"genre_scores_gemma":[0.9587409,0.002123014,0.03111479,0.0003841995,0.0000194611,0.00005875197,0.0008118314,0.000272102,0.006475047],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001333641,"threshold_uncertainty_score":0.004461527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01097065320888044,"score_gpt":0.2500573339343168,"score_spread":0.2390866807254363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}