{"id":"W1976156856","doi":"10.1016/j.bbamcr.2013.04.014","title":"Induction of mitochondrial biogenesis protects against caspase-dependent and caspase-independent apoptosis in L6 myoblasts","year":2013,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cell biology; Mitochondrion; Staurosporine; Apoptosis; Mitochondrial permeability transition pore; Mitochondrial biogenesis; Mitochondrial apoptosis-induced channel; Cytochrome c; XIAP; Biology; Mitochondrial ROS; Myocyte; Programmed cell death; Apoptosis-inducing factor; Caspase; Chemistry; Signal transduction; Biochemistry; Protein kinase C","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000599421,0.0005592456,0.0009544998,0.000396939,0.0006014334,0.0006367972,0.0005292769,0.0007417695,0.002376502],"category_scores_gemma":[0.0002926367,0.0003918998,0.0007885725,0.0004311302,0.0006539635,0.0004562959,0.0004606066,0.002142147,0.0006911397],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006938841,"about_ca_system_score_gemma":0.0007858973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001420703,"about_ca_topic_score_gemma":0.002370013,"domain_scores_codex":[0.9993613,0.0001064275,0.0001194749,0.0001170104,0.0001056474,0.0001900347],"domain_scores_gemma":[0.9994581,0.0001148882,0.0001066197,0.0001039692,0.00006023006,0.0001560681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001663871,0.0001907706,0.0002136558,0.000127285,0.00003172347,0.0001011928,0.00009959112,0.000108341,0.9958288,0.0002411842,0.0001878983,0.001205691],"study_design_scores_gemma":[0.0001519422,0.0006968298,0.0032757,0.00001877411,0.00003773351,0.0001119639,0.0001090078,0.0005474234,0.9928618,0.00009132845,0.002087775,0.000009637108],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914545,0.001996993,0.002782954,0.0005567342,0.0001314873,0.00007959861,0.001318795,0.0002432349,0.001435628],"genre_scores_gemma":[0.9922673,0.0007678788,0.001674663,0.0001472015,0.00003364242,0.0001317834,0.001517578,0.00005455812,0.003405458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002376502,"threshold_uncertainty_score":0.007950187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02286887655295857,"score_gpt":0.2832570746512022,"score_spread":0.2603881980982437,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}