{"id":"W1976171988","doi":"10.5539/cco.v1n1p1","title":"Practical Insights and Challenges in the Rational Use of Targeted Agents in Metastatic Clear Cell Renal Carcinoma","year":2012,"lang":"en","type":"article","venue":"Cancer and Clinical Oncology","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Renal cell carcinoma; Medicine; Targeted therapy; Immunotherapy; Oncology; Internal medicine; Carcinoma; Disease; Cancer research; Cancer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005911637,0.00009542736,0.0004282172,0.00005854695,0.00001666372,0.000003668443,0.00003047511,0.000115874,0.00004645257],"category_scores_gemma":[0.0002645628,0.00005839017,0.00004809858,0.00007408005,0.000195947,0.0000960314,0.00003401755,0.0002927496,0.000002429344],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008101721,"about_ca_system_score_gemma":0.0002259493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001264874,"about_ca_topic_score_gemma":0.0003687935,"domain_scores_codex":[0.9985314,0.0004849753,0.0004737815,0.0001919,0.0001409635,0.0001769741],"domain_scores_gemma":[0.9978918,0.001694035,0.0001200044,0.0001233997,0.00003793341,0.0001328177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002456363,0.002996214,0.9681658,0.0001634751,0.0001143819,0.0003829197,0.002747975,0.000002757469,0.000236652,0.001127418,0.0008097853,0.02079627],"study_design_scores_gemma":[0.003483643,0.001762014,0.9813359,0.00002116404,0.0001773029,0.00005196272,0.0004617723,0.0001501632,0.0001429851,0.00006487982,0.01229297,0.0000552304],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9823116,0.01179938,0.00000299664,0.004784148,0.0001031406,0.000317233,0.000003549236,0.000002366362,0.0006755736],"genre_scores_gemma":[0.9882198,0.01015048,0.0007013868,0.0007249031,0.0001141614,0.00004084279,0.000007450231,0.000006757853,0.00003423087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02074104,"threshold_uncertainty_score":0.2381082,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.412730657777344,"score_gpt":0.4621315939190053,"score_spread":0.04940093614166124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}