{"id":"W1976227120","doi":"10.1177/1535370215570828","title":"Antiproliferative activity of long chain acylated esters of quercetin-3- <i>O</i> -glucoside in hepatocellular carcinoma HepG2 cells","year":2015,"lang":"en","type":"article","venue":"Experimental Biology and Medicine","topic":"Phytochemicals and Antioxidant Activities","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Apoptosis; Chemistry; Hepatocellular carcinoma; DNA fragmentation; Cell growth; Biochemistry; Pharmacology; Acylation; Bioavailability; Toxicity; Glucoside; Quercetin; In vivo; Sorafenib; Programmed cell death; Cancer cell; Fatty acid; Biology; Antioxidant; Cancer; Cancer research; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007684031,0.0002061717,0.0001132413,0.0001479538,0.00006555222,0.00006615004,0.00006146634,0.0001097557,0.0006852066],"category_scores_gemma":[0.00006761752,0.000049046,0.0001673841,0.0001258953,0.00007391973,0.0001036425,0.00006729691,0.0001919482,0.000129606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008511666,"about_ca_system_score_gemma":0.0001245865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009011144,"about_ca_topic_score_gemma":0.001088483,"domain_scores_codex":[0.9999617,0.00001210769,0.000004117498,0.000004900321,0.000008049323,0.000008982213],"domain_scores_gemma":[0.9999547,0.000008662485,0.00001165297,0.000004892568,0.00001024861,0.000009799101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001805213,0.00002679328,0.0001234482,0.00002154422,0.0000040383,0.00002521279,0.000009178623,0.0000625044,0.9983425,0.00002040118,0.00001581567,0.001168025],"study_design_scores_gemma":[0.00002423806,0.001161623,0.003178299,0.000003912093,0.00001604434,0.00007641023,0.00002213065,0.000296548,0.9944546,0.00001663717,0.0007462499,0.000003447974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968024,0.001229935,0.0007174232,0.00003508622,0.00001378469,0.00001797026,0.0001621764,0.00001816309,0.001002995],"genre_scores_gemma":[0.997693,0.000617268,0.000732802,0.00003612033,0.000004810232,0.00001168088,0.0002509018,0.000004733539,0.000648724],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009011144,"threshold_uncertainty_score":0.002292275,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03024952393943656,"score_gpt":0.3121128652467945,"score_spread":0.2818633413073579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}