{"id":"W1976238224","doi":"10.1007/s00280-004-0817-y","title":"Novel vitamin E analogue and 9-nitro-camptothecin administered as liposome aerosols decrease syngeneic mouse mammary tumor burden and inhibit metastasis","year":2004,"lang":"en","type":"article","venue":"Cancer Chemotherapy and Pharmacology","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":false,"ca_institutions":"Brock University","funders":"National Institute of Environmental Health Sciences; National Cancer Institute","keywords":"Apoptosis; In vivo; In vitro; Camptothecin; DAPI; Mammary tumor; Molecular biology; Chemistry; Pharmacology; Transfection; Biochemistry; Biology; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001404753,0.0003312847,0.0003459777,0.00007513457,0.0001385153,0.00005380018,0.0001508629,0.0001729582,0.0001196692],"category_scores_gemma":[0.000007098056,0.000325015,0.00006765102,0.00009327158,0.0002078069,0.00001561073,0.0001180508,0.0001450572,0.000001391348],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000403023,"about_ca_system_score_gemma":0.0002769775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002185346,"about_ca_topic_score_gemma":0.00009039864,"domain_scores_codex":[0.998606,0.0000461151,0.000243773,0.0006336903,0.0000931223,0.0003773018],"domain_scores_gemma":[0.99923,0.00001984086,0.0001216823,0.0002128632,0.00005799912,0.0003576009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006808893,0.00007794192,0.00007038534,0.0000640596,0.0003764755,0.0000143868,0.0002087355,0.00001117897,0.9824673,0.0002511303,0.0001283983,0.01564913],"study_design_scores_gemma":[0.006658679,0.0007144705,0.0001041332,0.00002157525,0.0001469197,0.0002164226,0.00007062603,0.00002751571,0.9466562,0.0004034197,0.04458647,0.000393525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9833917,0.01208797,0.001308307,0.002307238,0.000198233,0.0004322729,0.0001768307,0.00002253144,0.00007491633],"genre_scores_gemma":[0.9638767,0.02173414,0.001236548,0.01192856,0.0005351148,0.0001769267,0.0000554627,0.00006085242,0.0003956598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04445807,"threshold_uncertainty_score":0.9999202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01531023479892969,"score_gpt":0.2888894467009151,"score_spread":0.2735792119019854,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}