{"id":"W1976246921","doi":"10.1111/j.1469-1809.2006.00267.x","title":"The Merits of Testing Hardy‐Weinberg Equilibrium in the Analysis of Unmatched Case‐Control Data: A Cautionary Note","year":2006,"lang":"en","type":"article","venue":"Annals of Human Genetics","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Genotyping; Statistic; Hardy–Weinberg principle; Statistics; Context (archaeology); Test (biology); Test statistic; Chi-square test; Statistical hypothesis testing; Econometrics; Mathematics; Computer science; Allele frequency; Genetics; Biology; Allele; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.3678654,0.001634938,0.005151061,0.00403424,0.00309143,0.006968114,0.009654347,0.008201935,0.001948682],"category_scores_gemma":[0.6067026,0.001073413,0.002836116,0.004583433,0.01992334,0.006960746,0.003455249,0.0247725,0.001456843],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001744009,"about_ca_system_score_gemma":0.0027556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004290094,"about_ca_topic_score_gemma":0.006097386,"domain_scores_codex":[0.6485839,0.2694043,0.03026997,0.01508319,0.03553235,0.001126248],"domain_scores_gemma":[0.2653051,0.6770026,0.01044464,0.02759229,0.01752524,0.002130077],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.003315311,0.0003990843,0.06299364,0.006324342,0.004072481,0.01288604,0.02255566,0.003248336,0.004973901,0.1369583,0.270547,0.4717259],"study_design_scores_gemma":[0.001290304,0.002239832,0.06797466,0.00964917,0.001953282,0.01949643,0.009331881,0.03629697,0.01108626,0.6100541,0.229176,0.001451209],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.0343744,0.02981192,0.4652006,0.409832,0.04787582,0.001168319,0.0009315499,0.001752019,0.009053387],"genre_scores_gemma":[0.2553849,0.009514809,0.4076733,0.2727449,0.04431821,0.002118357,0.0002648254,0.001130042,0.006850672],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.6321346,"threshold_uncertainty_score":0.7795345,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07702611504157066,"score_gpt":0.3585877522888192,"score_spread":0.2815616372472485,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}