{"id":"W1976274224","doi":"10.1021/bi900854z","title":"Targeting and Insertion of the Cholesterol-Binding Translocator Protein into the Outer Mitochondrial Membrane","year":2009,"lang":"en","type":"article","venue":"Biochemistry","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; U.S. Public Health Service","keywords":"Translocator protein; Mitochondrion; Translocase; Cytosol; Cell biology; Inner mitochondrial membrane; Chaperone (clinical); Protein targeting; Biology; Biochemistry; Bacterial outer membrane; Translocase of the outer membrane; Chemistry; Membrane protein; Mitochondrial membrane transport protein; Membrane; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000117646,0.0001359884,0.0001108454,0.00001219755,0.0001325685,0.00001942489,0.0002067847,0.0001997501,0.00001506419],"category_scores_gemma":[0.000108509,0.00008653646,0.00008073221,0.00007265723,0.0001241852,0.000003647875,0.00004672663,0.0001300599,0.000001793401],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008266996,"about_ca_system_score_gemma":0.00004398107,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009699681,"about_ca_topic_score_gemma":0.000004375558,"domain_scores_codex":[0.9991827,0.00006418066,0.0002179797,0.0002739046,0.0001118271,0.000149392],"domain_scores_gemma":[0.9994717,0.000007097542,0.0001045271,0.0003279593,0.00004407581,0.00004460077],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001103942,0.00002346268,0.00017003,0.00002518476,0.00001159858,3.960017e-7,0.0001379271,0.000003376468,0.9981992,0.0000129339,0.0005000339,0.000805478],"study_design_scores_gemma":[0.0004879771,0.00008429526,0.000262721,0.0000255205,0.00001480933,0.00001526189,0.00008208126,0.00001446314,0.9941562,0.00002108699,0.004732329,0.0001032071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972374,0.0003431726,0.0003935893,0.001234353,0.0002883839,0.0002551848,0.000006482821,0.000008954788,0.0002324996],"genre_scores_gemma":[0.9976588,0.00002663909,0.0004804918,0.0003774831,0.0005440871,0.00001857263,0.00003422522,0.000009813091,0.0008498355],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004232295,"threshold_uncertainty_score":0.3528854,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006346773247995719,"score_gpt":0.218305513217417,"score_spread":0.2119587399694213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}