{"id":"W1976286238","doi":"10.1021/ol800622e","title":"Distinctive Circular Dichroism Signature for 14-Helix-Bundle Formation by β-Peptides","year":2008,"lang":"en","type":"article","venue":"Organic Letters","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Circular dichroism; Signature (topology); Bundle; Helix (gastropod); Helix bundle; Crystallography; Stereochemistry; Protein structure; Biochemistry; Geometry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001022377,0.0002281779,0.0001048655,0.0003445827,0.0001519032,0.0001631346,0.000110534,0.0001712071,0.001133464],"category_scores_gemma":[0.000180953,0.000102769,0.00009168903,0.0001617005,0.0002321415,0.0001030864,0.0001016345,0.0002646117,0.0003730242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006619352,"about_ca_system_score_gemma":0.00005966191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005619354,"about_ca_topic_score_gemma":0.0000766094,"domain_scores_codex":[0.9999288,0.00001175449,0.000003460639,0.00002387297,0.00001829018,0.00001384155],"domain_scores_gemma":[0.9997761,0.0000443515,0.00007523357,0.00001420703,0.0000348582,0.00005534339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000039364,0.00001027981,0.00069989,0.00001682705,0.000002348275,0.00004690046,0.00002014895,0.00002189548,0.9980227,0.00005885705,0.00003365765,0.001027099],"study_design_scores_gemma":[0.00001970217,0.0005359569,0.03468812,0.000009393307,0.00001721165,0.001892419,0.00006916755,0.0009240838,0.9597875,0.0003286322,0.001714129,0.00001376818],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920233,0.0003752822,0.00457505,0.00006092845,0.00001458678,0.00001320755,0.0001384153,0.00006815501,0.002731103],"genre_scores_gemma":[0.9960984,0.00007991556,0.003075215,0.00006880722,0.00000796016,0.0000108746,0.0001849382,0.00001055471,0.0004633208],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001133464,"threshold_uncertainty_score":0.003791869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005230933029942424,"score_gpt":0.1915017875560407,"score_spread":0.1862708545260983,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}