{"id":"W1976306330","doi":"10.1016/j.ydbio.2010.08.029","title":"Protein kinase A regulates GDNF/RET-dependent but not GDNF/Ret-independent ureteric bud outgrowth from the Wolffian duct","year":2010,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Glial cell line-derived neurotrophic factor; Ureteric bud; Biology; Proto-Oncogene Proteins c-ret; Mesenchyme; Cell biology; Budding; Kidney development; Protein kinase A; Mesonephric duct; Morphogenesis; Embryonic stem cell; Kinase; Endocrinology; Mesenchymal stem cell; Receptor; Kidney; Biochemistry; Neurotrophic factors; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002803213,0.0004265943,0.0003123234,0.00005796378,0.0002861635,0.0000572833,0.0006948658,0.0006893748,0.0002460157],"category_scores_gemma":[0.00007052626,0.0002851089,0.0001617581,0.000134372,0.0003943289,0.000009125765,0.0004363732,0.0005873503,0.0001657992],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007223306,"about_ca_system_score_gemma":0.0003543761,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005581645,"about_ca_topic_score_gemma":0.0005661501,"domain_scores_codex":[0.9977046,0.0001432643,0.0004603653,0.0008548324,0.0002092956,0.0006276388],"domain_scores_gemma":[0.9990287,0.00002884483,0.000195735,0.0004761066,0.00007492812,0.0001956584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00027405,0.00005373491,0.003382182,0.000007766961,0.0002347995,0.00004925429,0.0001480096,0.000001828558,0.9882527,0.0001686865,0.0007483074,0.006678652],"study_design_scores_gemma":[0.00101776,0.0002278734,0.009122674,0.00002451047,0.00002906223,0.0001961112,0.0002303983,0.00000717565,0.9535576,0.0002810135,0.03479068,0.0005151553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949705,0.0005040868,0.00006332014,0.001392227,0.001156524,0.0005739922,0.0001823139,0.00004613265,0.001110917],"genre_scores_gemma":[0.9944364,0.0001432239,0.001005067,0.001111988,0.0005158826,0.0001447686,0.0008133381,0.00004575763,0.001783525],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03469514,"threshold_uncertainty_score":0.9999601,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006512535548877892,"score_gpt":0.2106346680654064,"score_spread":0.2041221325165285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}