{"id":"W1976402706","doi":"10.1021/bi900159d","title":"The Stem Cell Marker CD133 (Prominin-1) is Phosphorylated on Cytoplasmic Tyrosine-828 and Tyrosine-852 by Src and Fyn Tyrosine Kinases","year":2009,"lang":"en","type":"article","venue":"Biochemistry","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Université du Québec à Montréal","funders":"","keywords":"SH2 domain; Tyrosine phosphorylation; Proto-oncogene tyrosine-protein kinase Src; Tyrosine; FYN; Receptor tyrosine kinase; Phosphorylation; Biology; Tyrosine kinase; Cell biology; PTK2; Platelet-derived growth factor receptor; Molecular biology; Chemistry; Biochemistry; Signal transduction; Protein kinase A","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007211921,0.0003095229,0.0002098265,0.0004227653,0.0002346496,0.0002294995,0.0001213939,0.0001715118,0.0009226913],"category_scores_gemma":[0.00009259068,0.0001337173,0.0001623203,0.0002819357,0.0003069467,0.0001999576,0.0003035271,0.0002553621,0.0002031881],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002552631,"about_ca_system_score_gemma":0.0002794048,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009273099,"about_ca_topic_score_gemma":0.0012933,"domain_scores_codex":[0.999911,0.000006752349,0.000003515231,0.00001994781,0.00004072731,0.00001807091],"domain_scores_gemma":[0.9999539,0.00000469464,0.00001690231,0.00000182166,0.000005945038,0.0000167204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002296809,0.000003585355,0.0005952111,0.00001578305,0.000002207439,0.00007081986,0.00001529005,0.00001952583,0.9970407,0.0001022985,0.00003269417,0.00207882],"study_design_scores_gemma":[0.0000147216,0.0001629425,0.0338321,0.000007341168,0.00001797366,0.001048392,0.00007443123,0.00132095,0.9575609,0.0002087497,0.005742311,0.000009266151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940928,0.00123223,0.003269549,0.00007881886,0.000008534033,0.00001501981,0.0001716068,0.00008103062,0.001050464],"genre_scores_gemma":[0.9931688,0.0009456555,0.003458111,0.00003734569,0.00001021974,0.00002439963,0.0005020466,0.00001296624,0.001840485],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009273099,"threshold_uncertainty_score":0.003086686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007535546367641268,"score_gpt":0.2268960504082596,"score_spread":0.2193605040406183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}