{"id":"W1976448676","doi":"10.1097/tp.0b013e3181ff1493","title":"Extended Valganciclovir Prophylaxis in D+/R− Kidney Transplant Recipients is Associated With Long-Term Reduction in Cytomegalovirus Disease: Two-Year Results of the IMPACT Study","year":2010,"lang":"en","type":"article","venue":"Transplantation","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":208,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Valganciclovir; Medicine; Seroconversion; Cytomegalovirus; Internal medicine; Gastroenterology; Chemoprophylaxis; Betaherpesvirinae; Prospective cohort study; Human cytomegalovirus; Surgery; Ganciclovir; Immunology; Viral disease; Herpesviridae; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003774144,0.0007428745,0.001194768,0.0003442386,0.0001889082,0.0006837398,0.0003883588,0.0006181679,0.001173593],"category_scores_gemma":[0.002137998,0.0002642351,0.001181715,0.0003057393,0.0006870211,0.0005422028,0.0003801642,0.0009606938,0.0001716971],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003400673,"about_ca_system_score_gemma":0.0004690981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003295175,"about_ca_topic_score_gemma":0.0003791291,"domain_scores_codex":[0.9990024,0.0005694804,0.00007954901,0.0001154588,0.0001095715,0.0001235385],"domain_scores_gemma":[0.9978002,0.0006664372,0.000628527,0.0002425973,0.0001102418,0.0005520466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8663052,0.01756946,0.05009639,0.0003802759,0.001510876,0.0001322499,0.0001279022,0.0004575102,0.01329738,0.00005986578,0.0002340181,0.0498289],"study_design_scores_gemma":[0.2291334,0.5762812,0.1850469,0.0001033593,0.002639517,0.0003600418,0.0001097459,0.0008288604,0.004205679,0.0001152827,0.001122019,0.0000539757],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986005,0.0009292165,0.0001083256,0.00003371345,0.00001504622,0.00006732567,0.00005195201,0.000005906423,0.0001880688],"genre_scores_gemma":[0.99864,0.0005504809,0.0002181109,0.00009858171,0.00006792308,0.00005321276,0.0001884918,0.000002841202,0.0001803381],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003774144,"threshold_uncertainty_score":0.01995987,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01927510847249048,"score_gpt":0.3216206681204602,"score_spread":0.3023455596479697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}