{"id":"W1976461100","doi":"10.4161/viru.18639","title":"Mechanism of meningeal invasion by<i>Neisseria meningitidis</i>","year":2012,"lang":"en","type":"review","venue":"Virulence","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nautical Research Society","funders":"","keywords":"Extravasation; Biology; Blood–brain barrier; Cell biology; Neisseria meningitidis; Microbiology; Pilus; Intracellular; Cerebrospinal fluid; Leukocyte extravasation; Tight junction; Perivascular space; Biogenesis; Immunology; Bacteria; Central nervous system; Neuroscience; Virulence; Anatomy; Biochemistry; Cell adhesion molecule; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002362673,0.00046314,0.001279441,0.000140451,0.0002014888,0.00003069754,0.0005435995,0.0002645656,0.0001986187],"category_scores_gemma":[0.0001773916,0.000352643,0.0002920988,0.0005012612,0.0001646167,0.0002194053,0.0002949488,0.0003765883,0.0001660269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004139921,"about_ca_system_score_gemma":0.00008252906,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001054548,"about_ca_topic_score_gemma":8.854393e-7,"domain_scores_codex":[0.997734,0.0002216337,0.0006549126,0.000619915,0.000346173,0.0004234314],"domain_scores_gemma":[0.998405,0.0002875557,0.0006314715,0.000502705,0.00003714778,0.0001360739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001415058,0.00005854629,0.00000197983,0.007242735,0.00007174874,0.00000699633,0.0003154358,5.824394e-8,0.01796004,0.01438674,0.003594946,0.9563466],"study_design_scores_gemma":[0.00007538748,0.00006279014,2.592471e-7,0.001560215,0.0004186358,0.00004991918,0.00001144533,6.67443e-7,0.01766216,0.0004050946,0.9794144,0.000339014],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001828137,0.994368,0.000397744,0.000008256774,0.001378607,0.0003793737,0.0001875767,0.00008857424,0.003173581],"genre_scores_gemma":[0.001727548,0.9972205,0.0001323515,0.00009675899,0.0001641519,0.00007991306,0.00001227964,0.00005162187,0.0005149373],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9758195,"threshold_uncertainty_score":0.9998925,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09770747075963597,"score_gpt":0.3147747843712625,"score_spread":0.2170673136116265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}