{"id":"W1976461100","doi":"10.4161/viru.18639","title":"Mechanism of meningeal invasion by<i>Neisseria meningitidis</i>","year":2012,"lang":"en","type":"review","venue":"Virulence","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nautical Research Society","funders":"","keywords":"Extravasation; Biology; Blood–brain barrier; Cell biology; Neisseria meningitidis; Microbiology; Pilus; Intracellular; Cerebrospinal fluid; Leukocyte extravasation; Tight junction; Perivascular space; Biogenesis; Immunology; Bacteria; Central nervous system; Neuroscience; Virulence; Anatomy; Biochemistry; Cell adhesion molecule; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000308453,0.0007861478,0.0009651386,0.001970737,0.0003047705,0.0008506553,0.0007781016,0.0008562722,0.002629357],"category_scores_gemma":[0.0003081932,0.0002164252,0.0003401865,0.001323789,0.0004647665,0.001090579,0.0004938801,0.000892326,0.002164981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007046937,"about_ca_system_score_gemma":0.001042607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001543789,"about_ca_topic_score_gemma":0.001938887,"domain_scores_codex":[0.9999204,0.00001065116,0.00001316354,0.0000158673,0.00002931755,0.00001066995],"domain_scores_gemma":[0.9998913,0.00002682714,0.00002456979,0.000003670928,0.00003684622,0.00001677266],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009505332,0.0000746566,0.000285798,0.02060228,0.00008126775,0.0003868595,0.00006843065,0.0003366685,0.004677074,0.003936467,0.02456545,0.94489],"study_design_scores_gemma":[0.00001588768,0.00009941525,0.001705089,0.002851275,0.00009593542,0.002369742,0.00007708965,0.0001009011,0.001726196,0.002036563,0.9888999,0.00002197152],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001778441,0.9983755,0.00009817353,0.0001747136,0.00009271325,0.00000435958,0.00002050796,0.00000646117,0.001049709],"genre_scores_gemma":[0.0007430814,0.9984962,0.000116204,0.00005856597,0.00006906117,0.000004468347,0.00002380752,6.623628e-7,0.0004878671],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002629357,"threshold_uncertainty_score":0.008796096,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09770747075963597,"score_gpt":0.3147747843712625,"score_spread":0.2170673136116265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}