{"id":"W1976467817","doi":"10.1128/aem.07694-11","title":"Cloning, Baeyer-Villiger Biooxidations, and Structures of the Camphor Pathway 2-Oxo-Δ <sup>3</sup> -4,5,5-Trimethylcyclopentenylacetyl-Coenzyme A Monooxygenase of Pseudomonas putida ATCC 17453","year":2012,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre in Green Chemistry and Catalysis; McGill University; National Research Council Canada; Biotechnology Research Institute","funders":"Argonne National Laboratory; Basic Energy Sciences; National Research Council Canada; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Eli Lilly and Company; U.S. Department of Energy","keywords":"Pseudomonas putida; Stereochemistry; Monooxygenase; Cofactor; Flavin adenine dinucleotide; Substrate (aquarium); Escherichia coli; Biochemistry; Chemistry; Isomerase; Enzyme; Biology; Cytochrome P450","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001574161,0.0002056906,0.0002373173,0.00003859798,0.00008188932,0.000004928356,0.0001211826,0.0001965282,0.0000216557],"category_scores_gemma":[0.00001263504,0.0001518378,0.00006513952,0.00005526081,0.0003779905,0.000005601505,0.0002174001,0.0001017202,0.000002111382],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000011123,"about_ca_system_score_gemma":0.00001212861,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005149749,"about_ca_topic_score_gemma":0.000002209154,"domain_scores_codex":[0.9990814,0.00004533933,0.000269408,0.0003074103,0.00003867248,0.000257797],"domain_scores_gemma":[0.9994936,0.000007690384,0.0001378459,0.0002896322,0.000006441094,0.00006477281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003919668,0.00006803093,0.002713617,0.00002578891,0.00006721821,7.73623e-8,0.0001618272,0.0000548706,0.9952177,0.0001885102,0.0003185796,0.001144517],"study_design_scores_gemma":[0.0004361196,0.00005993452,0.006452049,0.0000059222,0.00003602191,0.00006918075,0.0002577854,0.000003047179,0.9724408,0.00002067847,0.02005484,0.0001636297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947038,0.004539727,0.0001322991,0.00003763017,0.0001098962,0.0002632719,0.0001731467,0.000005497996,0.00003475967],"genre_scores_gemma":[0.9976122,0.0009329112,0.0008904968,0.00008147318,0.0001426957,0.0000125197,0.0002083319,0.00001945188,0.0000998628],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02277697,"threshold_uncertainty_score":0.6191765,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003781979929297505,"score_gpt":0.1741346208344317,"score_spread":0.1703526409051342,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}