{"id":"W1976489564","doi":"10.1074/jbc.m412017200","title":"Vascular Endothelial Growth Factor (VEGF)-A165-induced Prostacyclin Synthesis Requires the Activation of VEGF Receptor-1 and -2 Heterodimer","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":126,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"","keywords":"Prostacyclin; Agonist; Vascular endothelial growth factor; Internal medicine; Endocrinology; Receptor; Kinase insert domain receptor; Prostaglandin; Vascular endothelial growth factor A; Vascular endothelial growth factor C; Biology; Chemistry; Medicine; VEGF receptors","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002600089,0.0002876011,0.0002970692,0.0001311767,0.0001176003,0.0003260137,0.000110732,0.0002454163,0.0009545098],"category_scores_gemma":[0.000195808,0.0001418033,0.0002591671,0.00009638158,0.0001381256,0.0001989191,0.0001451073,0.0003923936,0.0003326189],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002996624,"about_ca_system_score_gemma":0.0001892948,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003895715,"about_ca_topic_score_gemma":0.0005281203,"domain_scores_codex":[0.9998069,0.00003866217,0.00001510459,0.00004328108,0.0000423499,0.00005364743],"domain_scores_gemma":[0.9999052,0.0000170009,0.00002985516,0.000009197227,0.00001165035,0.00002706822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006976639,0.00002404997,0.0001554056,0.00003088575,0.000004003152,0.00005563429,0.000007232758,0.00002665948,0.9983802,0.0001181327,0.00004234064,0.00108573],"study_design_scores_gemma":[0.0001150934,0.00128094,0.02786914,0.00002166078,0.00002467919,0.001663604,0.00005111199,0.002498655,0.9567164,0.0002056604,0.009538511,0.00001466105],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9780625,0.0122059,0.005658323,0.0001635669,0.0001632008,0.000122021,0.0003597908,0.00008920463,0.003175443],"genre_scores_gemma":[0.9894973,0.002276271,0.004842213,0.0001224543,0.0000573277,0.00007922419,0.0005858209,0.000009717563,0.002529643],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009545098,"threshold_uncertainty_score":0.00319314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02612149925919397,"score_gpt":0.2627754703841255,"score_spread":0.2366539711249315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}