{"id":"W1976497124","doi":"10.1371/journal.ppat.1003420","title":"Glycan Masking of Plasmodium vivax Duffy Binding Protein for Probing Protein Binding Function and Vaccine Development","year":2013,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Research Council Canada","keywords":"Glycan; Biology; Epitope; Immunogenicity; Glycoprotein; Immunogen; Glycosylation; Plasmodium vivax; Binding site; Virology; Antibody; Computational biology; Monoclonal antibody; Biochemistry; Genetics; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001424919,0.000331606,0.0001733887,0.00009274434,0.0001207454,0.0001331829,0.000161919,0.0001843933,0.0004330974],"category_scores_gemma":[0.0001179964,0.0001045191,0.0001788857,0.0000980994,0.0001061239,0.0001132364,0.0001547133,0.0003700767,0.0001069986],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001753591,"about_ca_system_score_gemma":0.00009565971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006231314,"about_ca_topic_score_gemma":0.0007232743,"domain_scores_codex":[0.9999024,0.00002531263,0.000004460112,0.00001603144,0.00003073596,0.0000210878],"domain_scores_gemma":[0.9999464,0.00001064315,0.00001784916,0.000007413029,0.000009345511,0.0000084576],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002415901,0.000005634788,0.0001233095,0.000009687592,0.000001813113,0.00001592645,0.000005015208,0.00006481609,0.9993486,0.00001913634,0.0000055534,0.0003763022],"study_design_scores_gemma":[0.000005623046,0.0002468631,0.003324835,0.000002835116,0.000009894829,0.0002662825,0.00001492962,0.001462409,0.9937145,0.00003708776,0.0009109704,0.000003839703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958188,0.0002615381,0.003365226,0.00003236284,0.000005820472,0.00002081648,0.00006915512,0.000012708,0.0004135982],"genre_scores_gemma":[0.9937423,0.0003093908,0.0052719,0.00003945142,0.000003330872,0.00001604101,0.0001602047,0.000007429044,0.0004499283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006231314,"threshold_uncertainty_score":0.00144881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02181897673911013,"score_gpt":0.2264232297941495,"score_spread":0.2046042530550394,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}