{"id":"W1976499979","doi":"10.1074/jbc.m206588200","title":"Hormonal Regulation of Cystathionine β-Synthase Expression in Liver","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":144,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research; National Institutes of Health; Canadian Diabetes Association","keywords":"Cystathionine beta synthase; Transsulfuration; Endocrinology; Internal medicine; Insulin; Homocysteine; Streptozotocin; Cystathionine gamma-lyase; Biology; Chemistry; Diabetes mellitus; Enzyme; Cysteine; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002501388,0.00006364927,0.00022675,0.0000454205,0.00001226434,0.000003248826,0.00007079222,0.0001512937,0.001741247],"category_scores_gemma":[0.0003203414,0.00003799881,0.0000930891,0.0001169706,0.00007362371,0.00004285449,0.00002725469,0.0002973115,0.000004726637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004147661,"about_ca_system_score_gemma":0.00001885838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001163672,"about_ca_topic_score_gemma":6.364539e-8,"domain_scores_codex":[0.9991775,0.00002497771,0.0003605324,0.00007948856,0.000241844,0.0001156531],"domain_scores_gemma":[0.9994619,0.00007184406,0.0001597377,0.00008132521,0.0001310683,0.00009404775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003567414,0.0003498771,0.00657421,0.00005214453,0.00001008268,0.0001946965,0.00003215211,0.000003811102,0.9877241,0.00000100408,0.0009007601,0.003800434],"study_design_scores_gemma":[0.001321671,0.0005467288,0.09933413,0.0002363789,0.000009678248,0.0004348358,0.00005100185,0.0005258403,0.8966192,0.00003966352,0.0008273306,0.00005354011],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963232,0.001391241,0.00002794066,0.0002307003,0.00001157909,0.00003574172,0.000002383193,0.000002882897,0.001974297],"genre_scores_gemma":[0.9981434,0.0006777474,0.0005947307,0.00002014635,0.0001272793,6.446491e-7,0.000004261406,0.000003005925,0.0004288082],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09275992,"threshold_uncertainty_score":0.9991713,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05820564563741206,"score_gpt":0.2959250442337241,"score_spread":0.2377193985963121,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}