{"id":"W1976501240","doi":"10.1038/nbt.1516","title":"Characterization of human embryonic stem cells with features of neoplastic progression","year":2009,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":282,"is_retracted":false,"has_abstract":false,"ca_institutions":"Credit Valley Hospital; McMaster University","funders":"McMaster University","keywords":"Embryonic stem cell; Biology; Comparative genomic hybridization; Stem cell; Cell biology; Cancer research; Cancer stem cell; Genetics; Chromosome; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002179904,0.0001992673,0.0001377686,0.0003757444,0.0001537451,0.000339999,0.0001517429,0.0001784482,0.00124694],"category_scores_gemma":[0.0002952193,0.0001142788,0.0001670091,0.0002661361,0.0001474935,0.0002008601,0.0001585143,0.0002569569,0.0005489856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001209239,"about_ca_system_score_gemma":0.0001986473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005998537,"about_ca_topic_score_gemma":0.0005269083,"domain_scores_codex":[0.9999382,0.0000119937,0.000009276937,0.00000949504,0.00002218162,0.000008822954],"domain_scores_gemma":[0.9997889,0.00007876584,0.00001895273,0.00003898418,0.00004503454,0.00002927219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007279094,0.00001707267,0.0007122959,0.00001569904,0.000003551012,0.00009706668,0.00004627973,0.00006328839,0.9967836,0.0003267199,0.00002744885,0.001834125],"study_design_scores_gemma":[0.00001378411,0.0001849267,0.01298006,0.000004313174,0.00002596678,0.001057877,0.0000602338,0.0006711896,0.9787072,0.0001646778,0.006125611,0.000004186668],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981829,0.001147529,0.01072074,0.00009986466,0.00001450586,0.000146249,0.001243371,0.00008580684,0.004712895],"genre_scores_gemma":[0.9834332,0.001034755,0.006277876,0.0000650268,0.00001071706,0.00007926243,0.004085555,0.00004299965,0.004970568],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00124694,"threshold_uncertainty_score":0.004171371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004434019698835798,"score_gpt":0.254317639156499,"score_spread":0.2498836194576632,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}