{"id":"W1976518473","doi":"10.1002/jbm.a.31373","title":"Delivery of rapamycin by PLGA nanoparticles enhances its suppressive activity on dendritic cells","year":2007,"lang":"en","type":"article","venue":"Journal of Biomedical Materials Research Part A","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Materials science; PLGA; Nanoparticle; Nanotechnology; Drug delivery; Biomedical engineering; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.005713933,0.0001691507,0.0005821041,0.0004466694,0.0002013135,0.00003463869,0.0004788222,0.0003082845,0.002312741],"category_scores_gemma":[0.0007196428,0.0001213332,0.0001283499,0.000279673,0.0009977282,0.0001905433,0.0001124061,0.0005146193,0.0001953097],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006344431,"about_ca_system_score_gemma":0.0002317821,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003444415,"about_ca_topic_score_gemma":0.000001813049,"domain_scores_codex":[0.9960991,0.001665544,0.0008800579,0.0001861292,0.0003903907,0.000778796],"domain_scores_gemma":[0.9968877,0.001967131,0.0004167799,0.0002105471,0.0004249758,0.00009283859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009599087,0.000873037,0.00001147692,0.00006477465,0.0002354408,0.00006364573,0.0002475177,9.845822e-8,0.9693904,0.00001887465,0.01468093,0.004814723],"study_design_scores_gemma":[0.001666324,0.002784982,0.0006611884,0.0003290261,0.00001665543,0.00008617263,0.0002446699,1.22838e-7,0.9576265,0.00003311181,0.03644292,0.0001083175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928403,0.004905459,0.00002743925,0.0003954215,0.001476694,0.0001931188,0.000103387,0.000008683937,0.00004948389],"genre_scores_gemma":[0.9972643,0.001809477,0.00002184149,0.00005167001,0.0001322782,0.000005761521,0.000008612206,0.00001617432,0.0006898872],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02176199,"threshold_uncertainty_score":0.9985993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03449845616741869,"score_gpt":0.3400582379804402,"score_spread":0.3055597818130215,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}