{"id":"W1976528355","doi":"10.1016/j.jconrel.2006.04.013","title":"Histonefection: Novel and potent non-viral gene delivery","year":2006,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Histone; Gene delivery; Gene; Genetic enhancement; DNA; Gene transfer; Computational biology; Chemistry; Cell biology; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003153586,0.00038596,0.001674215,0.000210963,0.00007545138,0.00004895971,0.0002415928,0.000422892,0.00000967954],"category_scores_gemma":[0.00007986524,0.0002773681,0.001223001,0.0000634575,0.00006631951,0.000008288084,0.0000740086,0.0003836947,0.000008760341],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006080659,"about_ca_system_score_gemma":0.0004814472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001709343,"about_ca_topic_score_gemma":0.000005057715,"domain_scores_codex":[0.998127,0.0001031839,0.001042503,0.0002806328,0.0002169574,0.0002297002],"domain_scores_gemma":[0.9980718,0.0000359772,0.001151723,0.0002566024,0.000321886,0.000162036],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002266923,0.0004711165,0.000007463314,0.001695754,0.002458163,0.0003252956,0.000009610903,0.00009848922,0.01404274,0.000007466443,0.02286733,0.9557496],"study_design_scores_gemma":[0.006126788,0.0009984954,0.00001045445,0.001267879,0.001835852,0.001627442,0.000005193221,0.00002597557,0.0002201228,0.000006148937,0.9875153,0.0003603548],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004980484,0.9925317,0.001070493,0.00002495283,0.0006676418,0.0003602584,0.00002734324,0.000002947745,0.0003342482],"genre_scores_gemma":[0.003452688,0.9923629,0.0002320593,0.0001052773,0.001637457,0.0000167856,0.00004737126,0.00003933208,0.002106124],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9646479,"threshold_uncertainty_score":0.9999679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01306226983994043,"score_gpt":0.2687966003176653,"score_spread":0.2557343304777249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}