{"id":"W1976532358","doi":"10.1021/np200878s","title":"Dereplication, Residual Complexity, and Rational Naming: The Case of the <i>Actaea</i> Triterpenes","year":2012,"lang":"en","type":"article","venue":"Journal of Natural Products","topic":"Natural product bioactivities and synthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Marine Biosciences","funders":"National Center for Complementary and Integrative Health","keywords":"Triterpene; Terpene; Chemistry; Natural product; Stereochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006510236,0.00009816165,0.0001318518,0.00002504731,0.0001744706,0.00002294195,0.0001997863,0.0000534031,0.00000308485],"category_scores_gemma":[0.0006935163,0.00004822722,0.00006992617,0.0001056661,0.0002357119,0.00002729592,0.0001111882,0.0001958246,2.359342e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009462252,"about_ca_system_score_gemma":0.00006380892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001316754,"about_ca_topic_score_gemma":0.0000115653,"domain_scores_codex":[0.9991703,0.0001453438,0.000275068,0.0001197799,0.0001528159,0.0001366874],"domain_scores_gemma":[0.9989253,0.00005702479,0.0003687429,0.0002775832,0.0003366019,0.00003474026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000187562,0.00008410268,0.001991839,0.00004242713,0.0001111046,0.000004232632,0.0002134907,0.000002415673,0.976827,0.0007345033,0.01292064,0.006880712],"study_design_scores_gemma":[0.0002913956,0.00009229801,0.02080436,0.00001892284,0.00006334241,0.005592563,0.0002697037,0.000006330197,0.9561036,0.0003610866,0.01628277,0.0001136814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.973214,0.01332023,0.000005291577,0.01280061,0.000473476,0.0001336215,0.000008648372,0.000001293559,0.00004285579],"genre_scores_gemma":[0.9974731,0.0001318255,0.0005381782,0.0002486811,0.001314394,9.880525e-7,0.000003605779,0.000007327835,0.0002818542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02425917,"threshold_uncertainty_score":0.1966649,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02207435394227153,"score_gpt":0.2636859678154457,"score_spread":0.2416116138731741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}