{"id":"W1976532358","doi":"10.1021/np200878s","title":"Dereplication, Residual Complexity, and Rational Naming: The Case of the <i>Actaea</i> Triterpenes","year":2012,"lang":"en","type":"article","venue":"Journal of Natural Products","topic":"Natural product bioactivities and synthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Marine Biosciences","funders":"National Center for Complementary and Integrative Health","keywords":"Triterpene; Terpene; Chemistry; Natural product; Stereochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001267011,0.0003827525,0.0005253372,0.0005448145,0.0005302262,0.001500185,0.0007418836,0.0007004841,0.001075349],"category_scores_gemma":[0.00416253,0.0002627088,0.0006587835,0.0006714106,0.001793201,0.002436158,0.001001469,0.001223208,0.0004702724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006500119,"about_ca_system_score_gemma":0.0005359376,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005796026,"about_ca_topic_score_gemma":0.0005368753,"domain_scores_codex":[0.9989543,0.0003044534,0.00009763253,0.0003321401,0.0002407086,0.0000707217],"domain_scores_gemma":[0.9976271,0.001028925,0.0004204755,0.0007192386,0.000148509,0.0000557315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006852159,0.0001539958,0.007813939,0.0009210947,0.0001033795,0.003157785,0.001610838,0.05061439,0.4088264,0.2574958,0.002431422,0.2661859],"study_design_scores_gemma":[0.00005277109,0.0005198489,0.00585224,0.0001508179,0.0001473845,0.005063156,0.0009910478,0.251778,0.4260232,0.1988844,0.110308,0.0002292602],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5842136,0.004127492,0.3973653,0.001259247,0.0002034552,0.0001287234,0.0004788958,0.001026467,0.01119678],"genre_scores_gemma":[0.8073455,0.002246304,0.1862833,0.000270943,0.00007045876,0.00008996441,0.0006200835,0.0002330444,0.002840435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001500185,"threshold_uncertainty_score":0.006700695,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02207435394227153,"score_gpt":0.2636859678154457,"score_spread":0.2416116138731741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}