{"id":"W1976551878","doi":"10.1159/000138730","title":"Development of an Intravenous Desferrioxamine Mesylate Treatment Protocol for Swine: Monitoring of Desferrioxamine and Metabolites by High-Performance Liquid Chromatography","year":2008,"lang":"en","type":"article","venue":"Pharmacology","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Pharmacokinetics; Urine; Chemistry; Deferoxamine; Metabolism; Pharmacology; Chelation; Metabolite; High-performance liquid chromatography; Chromatography; Drug metabolism; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001400972,0.0002514893,0.0006307404,0.0001920172,0.0001288623,0.000002144078,0.00008187149,0.0001346335,0.00004284399],"category_scores_gemma":[0.00001014321,0.0001941395,0.00006320487,0.000207832,0.0002127554,0.00008054029,0.00003025886,0.00009881348,8.628376e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005906166,"about_ca_system_score_gemma":0.0002164028,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000436112,"about_ca_topic_score_gemma":0.000001451762,"domain_scores_codex":[0.9985903,0.00003647906,0.0005977406,0.0002826535,0.0001423793,0.0003504344],"domain_scores_gemma":[0.9993174,0.00004790878,0.0001867773,0.0001354452,0.0001390042,0.0001734728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002812849,0.001909331,0.005243625,0.0007185568,0.0006150383,0.00001729438,0.001715606,0.00002337951,0.9695765,0.000006859653,0.000077461,0.01728349],"study_design_scores_gemma":[0.01101055,0.004893909,0.01410245,0.00007040449,0.0002491979,0.0001019369,0.00008706378,0.0002556694,0.9618191,0.000002766609,0.007238052,0.0001688926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9721474,0.0004450358,0.00005708764,0.00005610383,0.0001063007,0.02709621,0.00001645835,0.00004223527,0.00003314669],"genre_scores_gemma":[0.952256,0.0005162747,0.01400509,0.0000338261,0.00008045616,0.03299454,0.00003323605,0.00003405742,0.00004656952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01989147,"threshold_uncertainty_score":0.7916778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02715503121888199,"score_gpt":0.3153051874585962,"score_spread":0.2881501562397142,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}