{"id":"W1976570893","doi":"10.1007/s10616-006-9004-9","title":"Toward genomic cell culture engineering","year":2006,"lang":"en","type":"article","venue":"Cytotechnology","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Bayer Canada; National Institute of General Medical Sciences; Bayer HealthCare; National Institutes of Health; Pfizer","keywords":"Biology; Computational biology; Genomics; Chinese hamster ovary cell; Transcriptome; Gene expression profiling; Proteome; DNA microarray; Bioprocess; Microarray; Gene; Genetics; Cell culture; Genome; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008793761,0.000501278,0.0004294112,0.0005879519,0.0004541432,0.001331196,0.0008104726,0.000632544,0.002177482],"category_scores_gemma":[0.0006141537,0.0004162788,0.000385026,0.000411519,0.0006822067,0.0008028364,0.0009954623,0.002446972,0.003027575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007374809,"about_ca_system_score_gemma":0.0005854978,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004104363,"about_ca_topic_score_gemma":0.0007634331,"domain_scores_codex":[0.999519,0.00009158848,0.00003000934,0.00009209281,0.0002197622,0.00004762372],"domain_scores_gemma":[0.999692,0.0001059177,0.00002254348,0.00007255897,0.00007399071,0.0000330728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002387527,0.0000679999,0.0003011462,0.0001571901,0.000008893096,0.0001187751,0.0001628597,0.0007898776,0.9226714,0.03524068,0.001343243,0.03911407],"study_design_scores_gemma":[0.00001416214,0.0001193092,0.0005492411,0.00005065205,0.00002698502,0.0004111577,0.00007109253,0.002933644,0.8719234,0.01007681,0.1138066,0.00001699164],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.06190003,0.004625109,0.9081723,0.001857717,0.0004710299,0.0003681877,0.0006353382,0.001281313,0.02068891],"genre_scores_gemma":[0.2609435,0.02189295,0.675001,0.001818756,0.0002458998,0.0008740598,0.004652377,0.0005767972,0.03399459],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002177482,"threshold_uncertainty_score":0.007284403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003860244553390234,"score_gpt":0.1913577413619565,"score_spread":0.1874974968085663,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}