{"id":"W1976575587","doi":"10.1074/jbc.m604482200","title":"A Control Switch for Prothrombinase","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Institutes of Health; University of Vermont; Cleveland Clinic; National Heart, Lung, and Blood Institute; Cleveland State University","keywords":"Prothrombinase; Chemistry; Medicine; Internal medicine; Thrombin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001727746,0.0003831371,0.0002470394,0.0001292393,0.0001761867,0.0007080228,0.0003929491,0.0002797726,0.004171799],"category_scores_gemma":[0.0002273057,0.0001434388,0.0001827923,0.00009811857,0.0002949804,0.0003545999,0.0002657867,0.0006619763,0.001269898],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004061427,"about_ca_system_score_gemma":0.0001541851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002193126,"about_ca_topic_score_gemma":0.0001957236,"domain_scores_codex":[0.9997379,0.00002446918,0.00001450619,0.0001160639,0.00005339241,0.00005360936],"domain_scores_gemma":[0.9998438,0.00002590489,0.00003380617,0.00003359216,0.00002120737,0.00004161542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005979123,0.00001903383,0.00008989175,0.00002229841,0.000002957574,0.00004969112,0.0000181768,0.0000456885,0.9927791,0.002970727,0.0002013606,0.003741233],"study_design_scores_gemma":[0.00003786743,0.0002674544,0.0009506245,0.000006932214,0.000009443395,0.0003077392,0.00002558832,0.001533423,0.9689775,0.0007763348,0.02709405,0.00001301754],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9107092,0.004023369,0.05345247,0.0007285654,0.001110144,0.0001544127,0.0006420983,0.001552358,0.02762726],"genre_scores_gemma":[0.9707541,0.0009083477,0.01062407,0.0002927232,0.0001051262,0.0001064,0.0004071613,0.0001321438,0.01666989],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004171799,"threshold_uncertainty_score":0.01395601,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02951616345093662,"score_gpt":0.2813502116254878,"score_spread":0.2518340481745512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}