{"id":"W1976585056","doi":"10.1038/cddis.2010.64","title":"Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98","year":2010,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":158,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research; Terry Fox Foundation","keywords":"EZH2; Nasopharyngeal carcinoma; microRNA; Carcinogenesis; Biology; Cancer research; Gene expression profiling; Polycomb-group proteins; PRC2; Enhancer; Regulation of gene expression; In silico; Tumor progression; Epigenetics; Gene expression; Gene; Genetics; Medicine; Repressor; Internal medicine; Radiation therapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006886857,0.0002181698,0.0002095248,0.00005314141,0.00005405825,0.00002684965,0.00008813573,0.0001777867,0.00008455223],"category_scores_gemma":[0.00003613435,0.0002170285,0.0000559602,0.00005733615,0.0001614107,0.00001240795,0.0001112828,0.00009660555,0.000001517403],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007708212,"about_ca_system_score_gemma":0.00009014124,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008023401,"about_ca_topic_score_gemma":0.00001600351,"domain_scores_codex":[0.9988413,0.00004475127,0.0002421077,0.000522697,0.0001073677,0.0002418011],"domain_scores_gemma":[0.9990166,0.00001365717,0.0001076979,0.0003406771,0.00005851834,0.0004628244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004692317,0.0001702711,0.0565351,0.0002332964,0.00001722681,0.000008095989,0.000099513,3.109347e-7,0.9337364,0.000009606002,0.008186554,0.0005343512],"study_design_scores_gemma":[0.002271856,0.0001563338,0.3522702,0.0000461209,0.00009594917,0.000005372737,0.0000199795,0.0002831978,0.6394611,0.0002698362,0.004776897,0.0003432278],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9812668,0.01764017,0.000007711806,0.0001156512,0.00006674668,0.0002990037,0.0004256072,0.000006762215,0.0001715341],"genre_scores_gemma":[0.9983957,0.0005083042,0.0001027574,0.0002118545,0.00004959405,0.00002297403,0.0003266181,0.00002057366,0.0003615757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.295735,"threshold_uncertainty_score":0.8850164,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00559818401351138,"score_gpt":0.2236240010714793,"score_spread":0.2180258170579679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}