{"id":"W1976595872","doi":"10.1128/jvi.02095-05","title":"Anti-V3 Humanized Antibody KD-247 Effectively Suppresses Ex Vivo Generation of Human Immunodeficiency Virus Type 1 and Affords Sterile Protection of Monkeys against a Heterologous Simian/Human Immunodeficiency Virus Infection","year":2006,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; School of Medicine, New York University; York University","keywords":"Biology; Virology; Simian immunodeficiency virus; Antibody; Heterologous; Virus; Neutralizing antibody; Epitope; Monoclonal antibody; Neutralization; Ex vivo; In vivo; Immunology; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001339498,0.0005163665,0.0002493114,0.0002386425,0.0001233582,0.0002256305,0.0001960861,0.0002713636,0.00100936],"category_scores_gemma":[0.0001016364,0.0001360771,0.0002175025,0.00005398833,0.0002034871,0.0001392632,0.0001153939,0.0006493361,0.0003890195],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002226045,"about_ca_system_score_gemma":0.0001852197,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003753573,"about_ca_topic_score_gemma":0.0004451772,"domain_scores_codex":[0.9998629,0.00002006281,0.000008743054,0.00002797281,0.00002627091,0.0000541161],"domain_scores_gemma":[0.9999028,0.00001943442,0.00002150433,0.00001381994,0.000008973148,0.00003347626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001172689,0.00008685609,0.0001509574,0.00001769487,0.000004364332,0.00004273378,0.000008473437,0.00002683312,0.9984919,0.00004850793,0.00005148007,0.0009529269],"study_design_scores_gemma":[0.00006629066,0.001770036,0.00442047,0.00000758208,0.00002305732,0.0006400914,0.0000186699,0.00100772,0.9897848,0.00005279324,0.002204327,0.000004235457],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969078,0.0006832387,0.001093309,0.00006301427,0.00002715302,0.00002350422,0.0001324976,0.00006936491,0.001000175],"genre_scores_gemma":[0.9971197,0.0003889254,0.0006600061,0.00005768354,0.0000201998,0.00001972182,0.0003508774,0.00001292348,0.001370034],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00100936,"threshold_uncertainty_score":0.003376722,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02401221959480272,"score_gpt":0.2956217132220385,"score_spread":0.2716094936272357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}