{"id":"W1976651445","doi":"10.1161/hypertensionaha.110.156158","title":"Negative Inotropy by Angiotensin II Is Mediated via Phosphoinositide 3-Kinase Alpha–Protein Kinase C-Coupled Signaling Pathway","year":2010,"lang":"en","type":"letter","venue":"Hypertension","topic":"Renin-Angiotensin System Studies","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Boniface Hospital","funders":"","keywords":"Phosphoinositide 3-kinase; Protein kinase C; Angiotensin II; Alpha (finance); Protein kinase A; Signal transduction; Kinase; Cell biology; Endocrinology; Chemistry; Internal medicine; Biology; Medicine; Protein kinase B; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005206815,0.0006913063,0.001217376,0.0002811058,0.0008480965,0.001067626,0.0006261808,0.01011276,0.00321168],"category_scores_gemma":[0.004446925,0.0002736859,0.0006927711,0.0001762699,0.00141723,0.001423503,0.0004429425,0.011809,0.001929439],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001431042,"about_ca_system_score_gemma":0.0005358875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006735695,"about_ca_topic_score_gemma":0.001396746,"domain_scores_codex":[0.9996527,0.0001006129,0.00003520212,0.00004869427,0.0000961915,0.00006664127],"domain_scores_gemma":[0.998879,0.0007255461,0.0001134506,0.00005751877,0.0000761092,0.0001483415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002617832,0.0005619422,0.0108712,0.0005135656,0.0003172812,0.2012749,0.0004359375,0.0003379451,0.01181858,0.01698483,0.6847236,0.06954237],"study_design_scores_gemma":[0.004888859,0.001598027,0.03396297,0.0006257416,0.0004701818,0.2389691,0.0007137939,0.006206583,0.01008289,0.05386342,0.6483558,0.0002626155],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.02954673,0.009787329,0.001379929,0.8952464,0.0375591,0.00005419823,0.0001339972,0.0002144175,0.02607789],"genre_scores_gemma":[0.3199518,0.01223335,0.001950323,0.4767083,0.1686245,0.0001545955,0.0001099128,0.00005783979,0.02020945],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.01011276,"threshold_uncertainty_score":0.01074415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01683758182392258,"score_gpt":0.2243814308378936,"score_spread":0.207543849013971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}