{"id":"W1976656452","doi":"10.1002/jlcr.879","title":"Base‐catalyzed deuterium and tritium labelling of 1‐biphenyl‐4‐ylpropane‐1,2‐dione and deuteration of aryl methyl ketones","year":2004,"lang":"en","type":"article","venue":"Journal of Labelled Compounds and Radiopharmaceuticals","topic":"Chemical Reactions and Isotopes","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Chemistry; Tritium; Deuterium; Aryl; Labelling; Catalysis; Biphenyl; Base (topology); Methyl group; Medicinal chemistry; Radiochemistry; Organic chemistry; Group (periodic table); Nuclear physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004417763,0.0005875629,0.0004467858,0.000455182,0.0002470199,0.000269493,0.000482705,0.0004335329,0.001859966],"category_scores_gemma":[0.0002488384,0.0002891,0.0001973752,0.0004085758,0.0003254799,0.0003251316,0.0003326944,0.0005906592,0.0007223375],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004561704,"about_ca_system_score_gemma":0.0004400663,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006610385,"about_ca_topic_score_gemma":0.001989164,"domain_scores_codex":[0.9997291,0.00005861716,0.0000171735,0.0000380466,0.00007681895,0.00008014407],"domain_scores_gemma":[0.9998245,0.00003214441,0.00005060908,0.00002585162,0.0000246696,0.00004218771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001583985,0.0000134713,0.00004980006,0.00007544934,0.000004463276,0.0001277627,0.00002789755,0.0001532996,0.9975932,0.0002162195,0.00006177065,0.001518117],"study_design_scores_gemma":[0.00001674288,0.0001361553,0.0002501555,0.000003160381,0.000005820674,0.0001094809,0.000006930188,0.0001310618,0.9973255,0.00003874338,0.001969524,0.000006726199],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.961714,0.006296451,0.02245883,0.0002303492,0.0002060089,0.000231258,0.001210976,0.0003189484,0.007333119],"genre_scores_gemma":[0.9629078,0.003954465,0.02045512,0.000100131,0.00003662349,0.0001222758,0.001004878,0.0001210751,0.01129766],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001859966,"threshold_uncertainty_score":0.006222188,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08759662683692337,"score_gpt":0.4086815204296083,"score_spread":0.3210848935926849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}