{"id":"W1976672229","doi":"10.1016/j.jaci.2014.12.1930","title":"Inherited CARD9 deficiency in otherwise healthy children and adults with Candida species–induced meningoencephalitis, colitis, or both","year":2015,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":219,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"National Center for Research Resources; National Institutes of Health; Astellas Pharma; Institut National de la Santé et de la Recherche Médicale; National Center for Advancing Translational Sciences; Agence Nationale de la Recherche; Cliniques Universitaires Saint-Luc; Regeneron Pharmaceuticals; ViiV Healthcare; Université Paris Descartes; Biogen; St. Giles Foundation; GlaxoSmithKline; Pfizer; Université de Montpellier; Gilead Sciences; Sanofi","keywords":"Meningoencephalitis; Candida albicans; Colitis; Biology; Candida glabrata; Immunology; Gastrointestinal tract; Medicine; Microbiology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002451158,0.000643237,0.000386202,0.001295347,0.0005532883,0.0005692434,0.0003701882,0.0007379994,0.002832092],"category_scores_gemma":[0.001695617,0.000311654,0.0002733159,0.0007273982,0.000623591,0.0005756151,0.0004894849,0.0004619705,0.0002983775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003834336,"about_ca_system_score_gemma":0.0003669549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003925507,"about_ca_topic_score_gemma":0.003774026,"domain_scores_codex":[0.9996508,0.00004769555,0.00005678698,0.00007808107,0.0000589565,0.0001075055],"domain_scores_gemma":[0.9994113,0.0001730039,0.0001844738,0.00001963207,0.00003451232,0.0001770407],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"case_report","study_design_scores_codex":[0.0007657403,0.0001179661,0.9429055,0.00003994379,0.00004172052,0.04934573,0.0004034312,0.00008797717,0.001993413,0.000161895,0.0005359763,0.003600755],"study_design_scores_gemma":[0.00005112217,0.0004778893,0.8836533,0.00004316598,0.00006525948,0.1127188,0.001460673,0.0003047311,0.0004916547,0.0001922126,0.0005216909,0.00001951899],"study_design_candidate":"case_report","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984248,0.0003011604,0.00003636375,0.00007587397,0.000009377814,0.000007244755,0.0001582784,0.000005639918,0.0009813297],"genre_scores_gemma":[0.9994664,0.000163915,0.0000642141,0.00004099603,0.00001323698,0.000003163108,0.0001172831,0.000001898572,0.0001290721],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003925507,"threshold_uncertainty_score":0.009474277,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04094366111904613,"score_gpt":0.3335405676423736,"score_spread":0.2925969065233275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}