{"id":"W1976673761","doi":"10.1007/s003350010238","title":"Transgenic mice for the preparation of puromycin-resistant primary embryonic fibroblast feeder layers for embryonic stem cell selection","year":2001,"lang":"en","type":"article","venue":"Mammalian Genome","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children's & Women's Health Centre of British Columbia; University of British Columbia","funders":"National Institute of Mental Health","keywords":"Embryonic stem cell; Biology; Puromycin; Transgene; Cell biology; Selection (genetic algorithm); Embryo; Genetically modified mouse; Fibroblast; Stem cell; Genetics; Cell culture; Gene; Protein biosynthesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001905644,0.0001706273,0.0001555894,0.00004101248,0.0001226233,0.00002416182,0.0001840963,0.0001191384,0.00001129182],"category_scores_gemma":[0.000005196081,0.0001513048,0.0001928613,0.0001069504,0.00002857256,0.000004946308,0.00002140904,0.00005111832,0.000002343319],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003724756,"about_ca_system_score_gemma":0.00008621341,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008736552,"about_ca_topic_score_gemma":0.00008397119,"domain_scores_codex":[0.9990405,0.00002202443,0.0002332915,0.0003129573,0.00009328852,0.000297899],"domain_scores_gemma":[0.9994835,0.00003206516,0.00009130371,0.0002516865,0.00009052976,0.00005087922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005226671,0.00003103824,0.0000328543,0.0001925598,0.00006441474,1.14082e-7,0.0001048805,0.01203905,0.9857156,0.00001510683,0.0005694418,0.0007123154],"study_design_scores_gemma":[0.001522988,0.001320232,0.004203744,0.00001794027,0.0001427716,0.00001334077,0.0002349523,0.001746495,0.8188105,0.00001590394,0.1716225,0.0003485956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8505455,0.002392539,0.145157,0.0002137288,0.0001636792,0.001175591,0.00007595023,0.00001822649,0.000257841],"genre_scores_gemma":[0.9916396,0.0001426976,0.001181754,0.00005590729,0.0002658391,0.0001826678,0.0001286469,0.00004245423,0.006360468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.171053,"threshold_uncertainty_score":0.6170033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009229808227061901,"score_gpt":0.2609108533244894,"score_spread":0.2516810450974276,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}