{"id":"W1976686309","doi":"10.1038/cdd.2008.95","title":"The chemokine CXCL12 promotes survival of postmitotic neurons by regulating Rb protein","year":2008,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":97,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institutes of Health; York University; Temple University; National Institute on Drug Abuse; Drexel University","keywords":"Neuroprotection; Cell biology; E2F; Biology; Chemokine receptor; Repressor; Small hairpin RNA; Transcription factor; Chemokine; Neurotoxicity; Neuroscience; Apoptosis; Chemistry; Receptor; Cell cycle; Gene knockdown; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009542537,0.0001088071,0.0001814,0.00002691973,0.0001810552,0.00001427267,0.00003703479,0.00005918225,0.00002420801],"category_scores_gemma":[0.0000838266,0.00007297812,0.00005411725,0.00007549159,0.0000442405,0.00003659026,0.00002453782,0.0001085623,0.000001019511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001323453,"about_ca_system_score_gemma":0.00002513926,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001867012,"about_ca_topic_score_gemma":0.000001302181,"domain_scores_codex":[0.9992395,0.00003236183,0.0002240161,0.0001542037,0.0001949634,0.0001549529],"domain_scores_gemma":[0.9995326,0.0000711996,0.0001181479,0.0001346719,0.00007036993,0.00007303728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008743243,0.0001584465,0.0858212,0.0001622685,0.00001972596,0.000001526456,0.0002280401,9.408528e-7,0.9110168,0.00009144928,0.0001681133,0.002244107],"study_design_scores_gemma":[0.001447465,0.0002580612,0.1483377,0.00008201275,0.00007553221,0.00001789392,0.00005971766,0.003578414,0.8456337,0.000133552,0.0002488854,0.0001270948],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978621,0.0005602545,0.0003513112,0.0002132227,0.00006337301,0.0003414814,0.000003562129,0.00002261165,0.0005820981],"genre_scores_gemma":[0.9983745,0.00009569906,0.0001194999,0.00001073507,0.00009052485,0.000008931317,0.00006499067,0.00001423802,0.001220945],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06538304,"threshold_uncertainty_score":0.2975961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01518829561927477,"score_gpt":0.2200173746465643,"score_spread":0.2048290790272895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}